Evidence map›Paper›PMID 28748957›Full record

ReviewNature reviews. Cardiology2018

Management of cardiovascular diseases in patients with obesity.

Carl J Lavie, Ross Arena, Martin A Alpert, Richard V Milani, Hector O Ventura

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 7 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 7 syntheses or guidelines pooled it, 217 citations in OpenAlex.

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  5. The obesity paradox in ST-segment elevation myocardial infarction patients: A meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Carl J LavieDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, Louisiana 70121, USA.
Ross ArenaDepartment of Physical Therapy, Department of Kinesiology and Nutrition, Integrative Physiology Laboratories, College of Applied Sciences, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, Illinois 60612, USA.
Martin A AlpertDivision of Cardiovascular Medicine, University of Missouri School of Medicine, One Hospital Drive, Columbia, Missouri 65212, USA.
Richard V MilaniDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, Louisiana 70121, USA.
Hector O VenturaDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, Louisiana 70121, USA.
University of Illinois Chicago · USUniversity of Missouri Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of cardiovascular diseases (CVD) in patients with obesity presents numerous challenges. Obesity has a negative effect on almost all of the major CVD risk factors, and adversely influences cardiovascular structure and function. Patients who are overweight or obese have a higher incidence of almost all CVDs compared with patients who are of normal weight. However, those who are overweight or obese seem to have a better short-term and medium-term prognosis after major CVD events and interventional procedures or cardiac surgeries than leaner patients, a phenomenon termed the 'obesity paradox'. In considering the mechanisms underlying this paradox, we review evidence of the deleterious consequences of obesity in patients with coronary heart disease, and the limited data on the benefits of weight loss in patients with CVD. Additional studies are needed on the efficacy of purposeful weight loss on cardiovascular outcomes to determine the ideal body composition for patients with CVD.

Indexed as

Obesity, MorbidCardiovascular DiseasesHumansWeight Loss

Identifiers

PMID28748957
OpenAlexW2741252257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.