Evidence map›Paper›PMID 28748494›Full record

ArticleInternational urology and nephrology2017

High glucose stimulates cell proliferation and Collagen IV production in rat mesangial cells through inhibiting AMPK-K

Bei Zhang, Yong-Quan Shi, Jun-Jie Zou, Xiang-Fang Chen, Wei Tang, Fei Ye, Zhi-Min Liu

Abstract read
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In one paragraph

Article in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Mesangial cell: A hub in lupus nephritis.Frontiers in immunology · 2022
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bei ZhangDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China.
Yong-Quan ShiDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China. shiyqwz@163.com.
Jun-Jie ZouDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China.
Xiang-Fang ChenDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China.
Wei TangDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China.
Fei YeDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China.
Zhi-Min LiuDepartment of Endocrinology, Shanghai Changzheng Hospital, No. 415, Fengyang Road, Huangpu District, Shanghai, 200003, People's Republic of China.
Shanghai Changzheng Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe present study investigated the putative mechanisms underlying effects of K

methodsRat mesangial cells were subjected to whole cell patch clamp to record the K

resultsWe found that HG was significant decreases in the expression of Kir6.1, SUB2A and SUB2B, three subunits of K

conclusionsTaken together, activating AMPK-K

Indexed as

Aminoimidazole CarboxamideAMP-Activated Protein KinasesAnimalsCell ProliferationCells, CulturedCollagen Type IVDecanoic AcidsDiabetic NephropathiesDiazoxideGlucoseHydroxy AcidsHypoglycemic AgentsKATP ChannelsKcnj11 ChannelMaleMesangial Cells5-hydroxydecanoic acidAbcc8 protein, ratAbcc9 protein, ratAICA ribonucleotideAminoimidazole CarboxamideAMP-Activated Protein KinasesCollagen Type IVDecanoic AcidsDiazoxideGlucoseHydroxy AcidsHypoglycemic AgentsKATP ChannelsKcnj11 ChannelPotassium Channels, Inwardly RectifyingRibonucleotidesSulfonylurea ReceptorsTissue Inhibitor of Metalloproteinase-2uK-ATP-1 potassium channelAMP-activated protein kinaseCell proliferationCollagen IVHigh glucoseKATP channel

Identifiers

PMID28748494
OpenAlexW2738197301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.