ArticleDermatology and therapy2017
The Burden of Chronic Urticaria from Brazilian Patients' Perspective.
Article in Dermatology and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- The Impact of Chronic Spontaneous Urticaria on Sleep-A Systematic Review.Dermatology and therapy · 2026Pooled it
- A Meta-Analysis of Observational Studies on the Association of Chronic Urticaria With Symptoms of Depression and Anxiety.Frontiers in medicine · 2020Pooled it
- A Systematic Review and Meta-Analysis of Health Utility Estimates in Chronic Spontaneous Urticaria.Frontiers in medicine · 2020Pooled it
- Pooled it
- The functional burden of chronic urticaria: Sleep quality, activity impairment and work productivity.Irish journal of medical science · 2026Article
- The Burden of Urticaria in the Middle East and North Africa Region From 1990 to 2021: A Systematic Analysis Based on the GBD Study 2021.Health science reports · 2026Article
- Clinical profile, prevalence, and burden of chronic spontaneous urticaria in the United States.The World Allergy Organization journal · 2025Article
- Incidence and Prevalence of Chronic Spontaneous Urticaria Among Adult and Pediatric Populations in the United States.Advances in therapy · 2025Article
- Urticaria Voices: Real-World Experience of Patients Living with Chronic Spontaneous Urticaria.Dermatology and therapy · 2025Article
- Cost-of-illness analysis of chronic urticaria clinical management in five countries of Latin America.Clinical and translational allergy · 2025Article
- Global, regional, and national levels and trends in burden of urticaria: A systematic analysis for the Global Burden of Disease study 2019.Journal of global health · 2024Article
- Burden of and Trends in Urticaria Globally, Regionally, and Nationally from 1990 to 2019: Systematic Analysis.JMIR public health and surveillance · 2023Article
- Urticaria: A Narrative Overview of Differential Diagnosis.Biomedicines · 2023Review
- Causal relationship between gut microbiota and urticaria: a bidirectional two-sample mendelian randomization study.Frontiers in microbiology · 2023Article
- Prospective analysis of clinical evolution in chronic urticaria: Persistence, remission, recurrence, and pruritus alone.The World Allergy Organization journal · 2022Article
- Prevalence, Clinical Manifestations, Treatment, and Clinical Course of Chronic Urticaria in Elderly: A Systematic Review.Journal of asthma and allergy · 2022Review
- Acupuncture and Related Therapies for Chronic Urticaria: A Critical Overview of Systematic Reviews.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Article
- Health-Related Utility of EQ-5D in Korean Adults With Chronic Urticaria: Mapping From Urticaria Outcome Measures.Allergy, asthma & immunology research · 2020Article
- Association between Chronic Urticaria andDermatology research and practice · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChronic urticaria (CU), a proxy for chronic spontaneous urticaria, has been associated with a negative impact on health-related quality of life (HRQoL) and costs, but there is limited evidence on the burden of CU in Brazil. The objective of this study was to estimate the prevalence of CU and assess the burden of CU on HRQoL and healthcare resource utilization (HRU) among adults in Brazil.
methodsThis retrospective, cross-sectional study, pooled data from the 2011, 2012, and 2015 National Health and Wellness Survey in Brazil (n = 36,000). Respondents (aged ≥18 years) diagnosed with and treated for CU provided data on demographics, health history, HRQoL (mental and physical health status) on Short-Form SF-36v2, presence of psychological complaints, work impairment, activity impairment, and HRU. Generalized linear models, controlling for covariates, examined differences between those treated for CU and matched controls on the outcome variables.
resultsThe prevalence of diagnosed CU was 0.41% (n = 249) and treated CU was 0.21% (n = 127). After adjustments, CU (currently treated for CU) was associated with worse mental functioning, physical functioning, and health utilities compared with controls (all p < 0.01). CU had over twice the odds of anxiety and sleep difficulties, over 1.5 times the work and activity impairment, twice the number of total physician visits, eight times the number of allergist visits, and twice the number of emergency room visits as controls (all p < 0.01).
conclusionsMany CU patients using prescription treatment experienced anxiety and sleep disturbances, poorer HRQoL, significant work and activity impairment, and high HRU, compared with matched general population controls. Findings suggest an unmet need for more effective treatment and management of CU in Brazil.
fundingNovartis Pharma AG and Genentech.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.