Evidence map›Paper›PMID 28748266›Full record

Observational studyClinical research in cardiology : official journal of the German Cardiac Society2017

Treatment of chronic heart failure in Germany: a retrospective database study.

Stefan Störk, Renate Handrock, Josephine Jacob, Jochen Walker, Frederico Calado, Raquel Lahoz, Stephan Hupfer, Sven Klebs

Open access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Noninvasive pulse contour analysis for determination of cardiac output in patients with chronic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2018
    Trial
  2. Sex-specific differences in disease severity and outcomes in left ventricular heart failure: a nationwide cohort study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  3. Article
  4. Systematic Literature Review of the Impact of Type 2 Diabetes and Heart Failure Guideline Adherence on Clinical and Economic Outcomes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Review
  5. Article
  6. Article
  7. Observational
  8. The underwhelming German life expectancy.European journal of epidemiology · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Higher prevalence of heart failure in rural regions: a population-based study covering 87% of German inhabitants.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
  17. Subclinical hypothyroidism and the development of heart failure: an overview of risk and effects on cardiac function.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Review
  18. Article
  19. Article
  20. Underestimated prevalence of heart failure in hospital inpatients: a comparison of ICD codes and discharge letter information.Clinical research in cardiology : official journal of the German Cardiac Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Stefan StörkComprehensive Heart Failure Centre Würzburg and Department of Internal Medicine I, University and University Hospital Würzburg, Am Schwarzenberg 15, 97078, Würzburg, Germany. Stoerk_S@ukw.de.
Renate HandrockNovartis Pharma GmbH, Nuremberg, Germany.
Josephine JacobElsevier Health Analytics, Berlin, Germany.
Jochen WalkerElsevier Health Analytics, Berlin, Germany.
Frederico CaladoNovartis Pharma AG, Basel, Switzerland.
Raquel LahozNovartis Pharma AG, Basel, Switzerland.
Stephan HupferNovartis Pharma GmbH, Nuremberg, Germany.
Sven KlebsNovartis Pharma GmbH, Nuremberg, Germany.
Novartis (Germany) · DENovartis (Switzerland) · CHUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence to treatment guidelines affects outcomes in patients with chronic heart failure (HF). We investigated patient pathways and treatment patterns for HF in Germany.

methodsThis retrospective study used anonymous healthcare claims data from the German Health Risk Institute on individuals with statutory health insurance. Patients with uninterrupted data from 1 January 2009 to 31 December 2013 or death (whichever occurred first), and ≥2 recorded HF-related diagnoses in 2011, were included. Patients with newly diagnosed HF were identified. Use of treatment patterns recommended by the European Society of Cardiology (2008) and German Nationale VersorgungsLeitlinien (2011) guidelines was evaluated.

resultsOf 123,925 patients with HF, 21.3% were newly diagnosed. Overall, 63.2% of new HF diagnoses were made in the ambulatory setting; 61.6% of these were made by family practitioners and 14.8% by cardiologists. In the ambulatory setting, family practitioners were primarily responsible for treatment; specialists in internal medicine (70.3% cardiologists) were mainly responsible for performing HF-related technical diagnostics. One-fifth (20.9%) of patients received a New York Heart Association (NYHA) classification; 45.1% of these received a guideline-based treatment pattern. Application of the recommended treatment pattern decreased with advancing disease severity (NYHA class IV: 21.1% application) and older age (≥90 years: 28.3% application).

conclusionsFamily practitioners play a key role in the diagnosis and initial treatment of HF in Germany. A substantial proportion of patients do not receive guideline-recommended pharmacotherapy. These findings should be reflected in the planning of national disease management programmes.

Indexed as

CardiologyDisease ManagementGuideline AdherenceHeart FailureAgedAged, 80 and overDatabases, FactualFemaleGermanyHumansMaleMiddle AgedMorbidityRetrospective StudiesTreatment OutcomeCardiologistCare pathwayGermanyGuidelinesHeart failureTreatment pattern

Identifiers

PMID28748266
PMCPMC5655600
OpenAlexW2738684027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.