Evidence map›Paper›PMID 28748250›Full record

ArticleDer Internist2018

[Disseminated osteolytic lesions in a 28-year-old refugee].

T Karrasch, H D Walmrath, M Kampschulte, D Steiner, W Seeger, W Padberg, U Sibelius, S Gattenlöhner, A Schäffler

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Der Internist, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

T KarraschKlinik und Poliklinik für Innere Medizin III, Universitätsklinikum Gießen und Marburg, Standort Gießen, 35392, Gießen, Deutschland. thomas.karrasch@innere.med.uni-giessen.de.
H D WalmrathKlinik und Poliklinik für Innere Medizin II, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
M KampschulteInstitut für Radiologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
D SteinerKlinik für Nuklearmedizin, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
W SeegerKlinik und Poliklinik für Innere Medizin II, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
W PadbergKlinik und Poliklinik für Allgemein‑, Viszeral- und Thoraxchirurgie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
U SibeliusKlinik und Poliklinik für Innere Medizin IV/V, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
S GattenlöhnerInstitut für Pathologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
A SchäfflerKlinik und Poliklinik für Innere Medizin III, Universitätsklinikum Gießen und Marburg, Standort Gießen, 35392, Gießen, Deutschland.
Universitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 28-year-old Syrian refugee presented with right-sided knee pain and progressive deterioration of the general condition over the past months. Laboratory diagnostics revealed severe hypercalcemia due to primary hyperparathyroidism, and computed tomography (CT) scanning demonstrated disseminated osteolytic lesions throughout the skeleton. Histologically, these lesions were characterized by multinuclear giant cells (defining these lesions as so-called brown tumors). Finally, surgical removal of a jugular mass allowed the histopathologic diagnosis of a sporadic parathyroid carcinoma. In the patient, this condition was associated with a mutation in the HPRT2 gene locus.

Indexed as

HypercalcemiaHyperparathyroidism, PrimaryOsteitis Fibrosa CysticaParathyroid NeoplasmsRefugeesAdultHumansGiant cellsHRPT2 geneHyperparathyroidismOsteolysisParathyroid neoplasm

Identifiers

PMID28748250
OpenAlexW2737897918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.