Evidence map›Paper›PMID 28748044›Full record

ArticleJournal of oral microbiology2017

Visualizing the dental biofilm matrix by means of fluorescence lectin-binding analysis.

Pune N Tawakoli, Thomas R Neu, Mette M Busck, Ute Kuhlicke, Andreas Schramm, Thomas Attin, Daniel B Wiedemeier, Sebastian Schlafer

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Biofilm volume and acidification within initial biofilms formed in situ on buccally and palatally exposed bracket material.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. The dental plaque biofilm matrix.Periodontology 2000 · 2021
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pune N TawakoliClinic of Preventive Dentistry, Periodontology and Cardiology, Centre of Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4219-3395
Thomas R NeuDepartment of River Ecology, Helmholtz Centre for Environmental Research - UFZ, Magdeburg, Germany.ORCID 0000-0001-6990-8787
Mette M BusckSection for Microbiology, Department of Bioscience, Aarhus University, Aarhus, Denmark.
Ute KuhlickeDepartment of River Ecology, Helmholtz Centre for Environmental Research - UFZ, Magdeburg, Germany.
Andreas SchrammSection for Microbiology, Department of Bioscience, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-7614-9616
Thomas AttinClinic of Preventive Dentistry, Periodontology and Cardiology, Centre of Dental Medicine, University of Zurich, Zurich, Switzerland.
Daniel B WiedemeierStatistical Services, Centre of Dental Medicine, University of Zurich, Zurich, Switzerland.
Sebastian SchlaferSection for Microbiology, Department of Bioscience, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-2463-1926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extracellular matrix is a poorly studied, yet important component of dental biofilms. Fluorescence lectin-binding analysis (FLBA) is a powerful tool to characterize glycoconjugates in the biofilm matrix. This study aimed to systematically investigate the ability of 75 fluorescently labeled lectins to visualize and quantify extracellular glycoconjugates in dental biofilms. Lectin binding was screened on pooled supragingival biofilm samples collected from 76 subjects using confocal microscopy. FLBA was then performed with 10 selected lectins on biofilms grown

Indexed as

Confocal laser scanning microscopydental biofilmsextracellular polymeric substancesglycoconjugateslectins

Identifiers

PMID28748044
PMCPMC5508396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.