ReviewJournal of oral microbiology2017
Fluoride resistance in
Review in Journal of oral microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 148 citations in OpenAlex.
- Effect of Xylitol and Fluoride Varnish on Biofilm and Saliva in Orthodontic Patients: A Triple-Blind Randomized Clinical Trial.Clinical and experimental dental research · 2025Trial
- Effect of fluoride varnishes on oral bacteria of preschool children with cavitated and non-cavitated carious lesions: randomized clinical trial.Scientific reports · 2023Trial
- Efficacy of aloe vera and probiotic mouthwashes vs fluoride mouthwash on Streptococcus mutans in plaque around brackets of orthodontic patients: a randomized clinical trial.The Angle orthodontist · 2023Trial
- Cytotoxicity, antibacterial efficacy, and fluoride content of commercial herbal toothpastes.BDJ open · 2026Article
- Anti-Cariogenic Potential of Lyophilized Cell-Free Supernatant of ProbioticJournal of microbiology and biotechnology · 2026Article
- Computational and preliminary screening of anti-caries active compounds of Caesalpinia sappan.Scientific reports · 2026Article
- Anti-Cariogenic Effect of Trans-Cinnamaldehyde in an In Vitro Mouse Jaw Explant Model.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Direct and transdentinal antibacterial activity of synthetic and biomimetic agents against different Streptococcus and Lactobacillus strains.European oral research · 2026Article
- Standardization of extraction, identification, and characterization of an immunoglobulin Y antibody: A potential inhibitor of cariogenic and endodontic microbiome.Journal of conservative dentistry and endodontics · 2025Article
- Microbial populations under fluoride stress: a metagenomic exploration from Indian soil.World journal of microbiology & biotechnology · 2025Article
- Advances and challenges in drug design against dental caries: Application ofJournal of pharmaceutical analysis · 2025Review
- Molecular Insights into Fluoride Ion Uptake and Selectivity in the CLCF Fluoride/Proton Antiporter.The journal of physical chemistry. B · 2025Article
- Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries.Medical review (2021) · 2025Review
- Comparative Assessment of Efficacy of Cranberry Extract Mouthwash and Fluoride Mouthwash onInternational journal of clinical pediatric dentistry · 2025Article
- Enzymatic Degradation of PFAS: Current Status and Ongoing Challenges.ChemSusChem · 2025Review
- Sodium houttuyfonate inhibits the cariogenic virulence ofJournal of oral microbiology · 2025Article
- Evaluation of the Antibacterial and Anti-Biofilm Activity of Chitosan-Arginine Nanoparticles and Sodium Fluoride againstInternational journal of molecular and cellular medicine · 2025Article
- Unlocking nature's brilliance: using Antarctic extremophile Shewanella baltica to biosynthesize lanthanide-containing nanoparticles with optical up-conversion.Journal of nanobiotechnology · 2024Article
- Enhancement of Fluoride's Antibacterial and Antibiofilm Effects against OralAntibiotics (Basel, Switzerland) · 2024Article
- Defluorination of monofluorinated alkane by Rhodococcus sp. NJF-7 isolated from soil.AMB Express · 2024Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For decades, fluoride has been used extensively as an anti-caries agent. It not only protects dental hard tissue, but also inhibits bacterial growth and metabolism. The antimicrobial action of fluoride is shown in three main aspects: the acidogenicity, acidurance, and adherence to the tooth surface. To counteract the toxic effect of fluoride, oral bacteria are able to develop resistance to fluoride through either phenotypic adaptation or genotypic changes. Strains that acquire fluoride resistance through the latter route show stable resistance and can usually resist much higher fluoride levels than the corresponding wild-type strain. This review summarizes the characteristics of fluoride-resistant strains and explores the mechanisms of fluoride resistance, in particular the recent discovery of the fluoride exporters. Since the fluoride resistance of the cariogenic bacterium
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.