Evidence map›Paper›PMID 28748030›Full record

ArticleJournal of oral microbiology2017

16S rDNA analysis of periodontal plaque in chronic obstructive pulmonary disease and periodontitis patients.

Xingwen Wu, Jiazhen Chen, Meng Xu, Danting Zhu, Xuyang Wang, Yulin Chen, Jing Wu, Chenghao Cui, Wenhong Zhang, Liying Yu

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Advances in the study of the relationship betweenFrontiers in cell and developmental biology · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. PeriodontopathogensPathogens (Basel, Switzerland) · 2023
    Review
  17. [Oral Microbiome and Systemic Diseases].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Review
  18. [The Relationship Between Oral Microbiota and Chronic Obstructive Pulmonary Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xingwen WuDepartment of Dentistry, Huashan Hospital, Fudan University, Shanghai, P.R. China.ORCID 0000-0002-6943-7185
Jiazhen ChenDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Meng XuDepartment of Dentistry, Huashan Hospital, Fudan University, Shanghai, P.R. China.ORCID 0000-0002-1223-7668
Danting ZhuDepartment of Dentistry, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Xuyang WangDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, P.R. China.ORCID 0000-0003-3589-5126
Yulin ChenDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Jing WuDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Chenghao CuiDepartment of Dentistry, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Wenhong ZhangDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Liying YuDepartment of Dentistry, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Fudan University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated if chronic obstructive pulmonary disease (COPD) is correlated with periodontitis via periodontal microbiota and if certain bacteria affect periodontitis as well as COPD. Moreover, the study investigated whether suffering from COPD is associated with a decrease in the richness and diversity of periodontal microbiota. Subgingival plaque was obtained from 105 patients. Bacterial DNA was isolated from 55 COPD and 50 non-COPD participants (either with or without periodontitis). 16S rRNA gene metagenomic sequencing was used to characterize the microbiota and to determine taxonomic classification. In the non-periodontitis patients, suffering from COPD resulted in a decrease in bacteria richness and diversity in the periodontal microenvironment. An increase in the genera

Indexed as

16s rRNA genechronic obstructive pulmonary diseasechronic periotontal diseasehigh-throughput sequencingOral microbiotasubgingival plaque

Identifiers

PMID28748030
PMCPMC5508401
OpenAlexW2626365750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.