Evidence map›Paper›PMID 28747521›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Novel

Songye Li, Zhengxin Cai, Ming-Qiang Zheng, Daniel Holden, Mika Naganawa, Shu-Fei Lin, Jim Ropchan, David Labaree, Michael Kapinos, Teresa Lara-Jaime and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Optimization of a Nucleophilic Two-Step Radiosynthesis of 6-International journal of molecular sciences · 2023
    Article
  2. Characterization in nonhuman primates of (R)-[European journal of nuclear medicine and molecular imaging · 2022
    Article
  3. Review
  4. Evaluation of Specific Binding of [ACS medicinal chemistry letters · 2021
    Article
  5. Article
  6. Article
  7. Quantitative Rodent Brain Receptor Imaging.Molecular imaging and biology · 2020
    Review
  8. A Survey of Molecular Imaging of Opioid Receptors.Molecules (Basel, Switzerland) · 2019
    Review
  9. Development and In Vivo Evaluation of a κ-Opioid Receptor Agonist as a PET Radiotracer with Superior Imaging Characteristics.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  10. Article
  11. Chemistry for Positron Emission Tomography: Recent Advances inAngewandte Chemie (International ed. in English) · 2019
    Review
  12. Radiosynthesis of [ACS medicinal chemistry letters · 2018
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Songye LiPET Center, Yale University School of Medicine, New Haven, Connecticut; and songye.li@yale.edu.
Zhengxin CaiPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Ming-Qiang ZhengPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Daniel HoldenPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Mika NaganawaPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Shu-Fei LinPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Jim RopchanPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
David LabareePET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Michael KapinosPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Teresa Lara-JaimePET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Antonio NavarroEli Lilly and Company, Indianapolis, Indiana.
Yiyun HuangPET Center, Yale University School of Medicine, New Haven, Connecticut; and.
Yale University · USEli Lilly (United States) · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The κ-opioid receptor (KOR) has been implicated in depression, addictions, and other central nervous system disorders and, thus, is an important target for drug development. We previously developed several

Indexed as

Fluorine RadioisotopesAnimalsBenzamidesChemistry Techniques, SyntheticIsotope LabelingMacaca mulattaPositron-Emission TomographyPyridinesRadioactive TracersRadiochemistryReceptors, Opioid, kappaBenzamidesFluorine-18Fluorine RadioisotopesLY2459989PyridinesRadioactive TracersReceptors, Opioid, kappa18F-LY2459989antagonistnonhuman primatesPETκ-opioid receptor

Identifiers

PMID28747521
PMCPMC5750518
OpenAlexW2738357782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.