Evidence map›Paper›PMID 28747501›Full record

ArticleJournal of virology2017

Murine Gammaherpesvirus 68 Expressing Kaposi Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen (LANA) Reveals both Functional Conservation and Divergence in LANA Homologs.

Arundhati Gupta, Darby G Oldenburg, Eduardo Salinas, Douglas W White, J Craig Forrest

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. KSHV LANA acetylation-selective acidic domain reader sequence mediates virus persistence.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  11. Review
  12. Article
  13. Journal of virology · 2018
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Arundhati GuptaDept. of Microbiology and Immunology and Center for Microbial Pathogenesis and Host Inflammatory Responses, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Darby G OldenburgGundersen Medical Foundation, La Crosse, Wisconsin, USA.
Eduardo SalinasDept. of Microbiology and Immunology and Center for Microbial Pathogenesis and Host Inflammatory Responses, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Douglas W WhiteGundersen Medical Foundation, La Crosse, Wisconsin, USA.
J Craig ForrestDept. of Microbiology and Immunology and Center for Microbial Pathogenesis and Host Inflammatory Responses, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA JCForrest@uams.edu.
University of Arkansas for Medical Sciences · USGundersen Health System · US

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
Gammaherpesvirus interactions with host tumor suppressor p53R01CA167065 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI James Craig Forrest · 2014 to 2026
$3.8M
NCI NIH HHS R01 CA167065NIGMS NIH HHS P20 GM103625
6 · The paper itself

Abstract

Latency-associated nuclear antigen (LANA) is a multifunctional protein encoded by members of the

Indexed as

3T3 CellsAnimalsAntigens, ViralCell LineFemaleGene Knock-In TechniquesHEK293 CellsHerpesvirus 8, HumanHumansImmediate-Early ProteinsMaleMiceMice, Inbred C57BLNuclear ProteinsPromoter Regions, GeneticRhadinovirusAntigens, ViralImmediate-Early Proteinslatency-associated nuclear antigenNuclear ProteinsRta protein, Human herpesvirus 8Trans-ActivatorsgammaherpesvirusKaposi sarcoma-associated herpesvirusLANAlatency-associated nuclear antigenlatent infectionlytic infectionmurid herpesvirus 4murine gammaherpesvirus 68small animal model

Identifiers

PMID28747501
PMCPMC5599733
OpenAlexW2737171267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.