ArticleJournal of neurophysiology2017
Isoflurane, ketamine-xylazine, and urethane markedly alter breathing even at subtherapeutic doses.
Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 48 citations in OpenAlex.
- Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice.Psychopharmacology · 2026Article
- Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Spontaneous peripheral oxygen desaturation and apnea events in mice vary by strain and inspired oxygen level.bioRxiv : the preprint server for biology · 2025Article
- Chronic sustained hypoxia alters the pattern of diaphragm electrical activity in anaesthetized rats.Experimental physiology · 2025Article
- Cardiovascular function and autonomic regulation in urethane-anesthetized and conscious mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Interactions between Arousal State and COThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Sodium Leak Channel in Glutamatergic Neurons of the Lateral Parabrachial Nucleus Helps to Maintain Respiratory Frequency Under Sevoflurane Anesthesia.Neuroscience bulletin · 2024Article
- O-GlcNAcylation levels remain stable regardless of the anaesthesia in healthy rats.Scientific reports · 2024Article
- Closed-loop cervical epidural stimulation partially restores ipsilesional diaphragm EMG after acute CRespiratory physiology & neurobiology · 2024Article
- Contributions of carotid bodies, retrotrapezoid nucleus neurons and preBötzinger complex astrocytes to the COThe Journal of physiology · 2024Article
- Seizures Cause Prolonged Impairment of Ventilation, COThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Basic physiological effects of ketamine-xylazine mixture as a general anesthetic preparation for rodent surgeries.Brain research · 2023Article
- Parabrachial tachykinin1-expressing neurons involved in state-dependent breathing control.Nature communications · 2023Article
- Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge.PloS one · 2023Article
- Evaluation of Active Warming and Surgical Draping for Perioperative Thermal Support in Laboratory Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- A leak-free head-out plethysmography system to accurately assess lung function in mice.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Modulation of lymphatic transport in the central nervous system.Theranostics · 2022Review
- Mouse Anesthesia: The Art and Science.ILAR journal · 2021Review
- Impact of Inhaled Oxygen on Reactive Oxygen Species Production and Oxidative Damage during Spontaneous Ventilation in a Murine Model of Acute Renal Ischemia and Reperfusion.Medical research archives · 2021Article
- Effects of Oxygen Supplementation on Injectable and Inhalant Anesthesia in C57BL/6 Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Anesthetics are widely used for animal research on respiratory control in vivo, but their effect on breathing and CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.