Observational studyNeurology2017
Magnesium, hemostasis, and outcomes in patients with intracerebral hemorrhage.
Observational study in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 63 citations in OpenAlex.
- Administration of Calcium and Magnesium in Acute Intracerebral Hemorrhage Patients: Assessing Safety and Feasibility.Journal of Korean medical science · 2025Trial
- Magnesium and Hematoma Expansion in Intracerebral Hemorrhage: A FAST-MAG Randomized Trial Analysis.Stroke · 2024Trial
- Magnesium Sulfate and Hematoma Expansion: An Ancillary Analysis of the FAST-MAG Randomized Trial.Stroke · 2022Trial
- The role of stem cells and their engineering strategies in the repair of nerve damage in intracerebral hemorrhage.Cell & bioscience · 2026Review
- Association of low magnesium status with incident intracranial hemorrhage: a matched-control database study.Frontiers in nutrition · 2026Article
- The relationship between hypomagnesemia and ICU mortality in severe hemorrhagic stroke patients: an observational multicentre study on eICU database.BMC cardiovascular disorders · 2025Observational
- Application of deep learning and radiomics in the prediction of hematoma expansion in intracerebral hemorrhage: a fully automated hybrid approachDiagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- Prognostic value of day-of-event serum calcium and magnesium for predicting 1-year prognosis after intracerebral hemorrhage.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Blood-Based Biomarkers in Intracerebral Hemorrhage.Journal of clinical medicine · 2023Review
- Association of Serum Magnesium with Gastrointestinal Bleeding in Peritoneal Dialysis Patients: a Multicentre Retrospective Study.Biological trace element research · 2023Article
- Initial Serum Magnesium Level Is Associated with Mortality Risk in Traumatic Brain Injury Patients.Nutrients · 2022Article
- Therapeutic Approaches to the Neurologic Manifestations of COVID-19.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Article
- Underlying microangiopathy and functional outcome of simultaneous multiple intracerebral hemorrhage.Frontiers in aging neuroscience · 2022Article
- Low Serum Magnesium Levels Are Associated With Hemorrhagic Transformation After Mechanical Thrombectomy in Patients With Acute Ischemic Stroke.Frontiers in neurology · 2022Article
- Neuroprotective Therapies for Spontaneous Intracerebral Hemorrhage.Neurocritical care · 2021Review
- Article
- Identifying Modifiable Predictors of Patient Outcomes After Intracerebral Hemorrhage with Machine Learning.Neurocritical care · 2021Article
- Observational
- Serum osmolality, cerebrospinal fluid specific gravity and overt hepatic encephalopathy severity in patients with liver failure.Liver international : official journal of the International Association for the Study of the Liver · 2020Article
- Elevated Cerebrospinal Fluid Protein Is Associated with Unfavorable Functional Outcome in Spontaneous Subarachnoid Hemorrhage.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020Observational
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
objectiveWe tested the hypothesis that admission serum magnesium levels are associated with hematoma volume, hematoma growth, and functional outcomes in patients with intracerebral hemorrhage (ICH).
methodsPatients presenting with spontaneous ICH were enrolled in an observational cohort study that prospectively collected demographic, clinical, laboratory, radiographic, and outcome data. We performed univariate and adjusted multivariate analyses to assess for associations between serum magnesium levels and initial hematoma volume, final hematoma volume, and in-hospital hematoma growth as radiographic measures of hemostasis, and functional outcome measured by the modified Rankin Scale (mRS) at 3 months.
resultsWe included 290 patients for analysis. Admission serum magnesium was 2.0 ± 0.3 mg/dL. Lower admission magnesium levels were associated with larger initial hematoma volumes on univariate (
conclusionsThese data support the hypothesis that magnesium exerts a clinically meaningful influence on hemostasis in patients with ICH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.