Evidence map›Paper›PMID 28747384›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Feeding Releases Endogenous Opioids in Humans.

Jetro J Tuulari, Lauri Tuominen, Femke E de Boer, Jussi Hirvonen, Semi Helin, Pirjo Nuutila, Lauri Nummenmaa

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Trial
  5. Trial
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Pleasurable music activates cerebral µ-opioid receptors: a combined PET-fMRI study.European journal of nuclear medicine and molecular imaging · 2025
    Article
  12. Article
  13. Why friendship and loneliness affect our health.Annals of the New York Academy of Sciences · 2025
    Review
  14. Current perspectives on brain circuits involved in food addiction-like behaviors.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Jetro J TuulariTurku PET Centre.
Lauri TuominenTurku PET Centre.
Femke E de BoerTurku PET Centre.
Jussi HirvonenTurku PET Centre.
Semi HelinTurku PET Centre.
Pirjo NuutilaTurku PET Centre.ORCID 0000-0001-9597-338X
Lauri NummenmaaTurku PET Centre, latanu@utu.fi.ORCID 0000-0002-2497-9757
Nature Conservation Centre · TRHarvard University · USTurku University Hospital · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endogenous opioid system supports a multitude of functions related to appetitive behavior in humans and animals, and it has been proposed to govern hedonic aspects of feeding thus contributing to the development of obesity. Here we used positron emission tomography to investigate whether feeding results in hedonia-dependent endogenous opioid release in humans. Ten healthy males were recruited for the study. They were scanned with the μ-opioid-specific ligand [

Indexed as

AdultAnalgesics, OpioidBrainCarbon RadioisotopesEatingFastingFeeding BehaviorFentanylHumansMaleOpioid PeptidesPleasurePositron-Emission TomographyReceptors, Opioid, muSatiety ResponseYoung AdultAnalgesics, OpioidCarbon RadioisotopescarfentanilFentanylOpioid PeptidesReceptors, Opioid, mucarfentanilemotionfeedingneuroreceptorsopioidspositron emission tomography

Identifiers

PMID28747384
PMCPMC6596790
OpenAlexW2737665004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.