Evidence map›Paper›PMID 28746751›Full record

ArticleCancer2017

Cancer donor preferences for disposition of their biospecimens after biobank closure.

Samuel C Allen, Margie D Dixon, Jeffrey M Switchenko, Rebecca D Pentz

Open access · greenAbstract read
In one paragraph

Article in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samuel C AllenDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.
Margie D DixonDepartment of Hematology and Oncology, Emory University School of Medicine, Atlanta, Georgia.
Jeffrey M SwitchenkoDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.
Rebecca D PentzDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.ORCID http://orcid.org/0000-0003-4338-6663
Emory University · US

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
Interactive multimedia consent for biobankingR01HG008348 · NHGRI · UNIVERSITY OF IOWA · PI KLEIN, DAVID WASHINGTON, SIMON, CHRISTIAN MICHAEL · 2015 to 2017
$1.8M
NCI NIH HHS P30 CA138292NHGRI NIH HHS R01 HG008348
6 · The paper itself

Abstract

backgroundBiobank funding is unstable and biobank administrators are concerned about loss of funding and subsequent biobank closure. Nevertheless, only a minority of biobanks have policies regarding the distribution or destruction of tissue if the biobank were to close. To the authors' knowledge, the current study is the first to report on the preferences of oncology biospecimen donors regarding the handling of their biospecimens in the event of biobank closure.

methodsA total of 98 biospecimen donors who were diagnosed with cancer at the Georgia Cancer Center for Excellence at Grady Memorial Hospital or the Winship Cancer Institute were interviewed concerning their preferences for the handling of their biospecimens in the event of biobank closure.

resultsThe majority of biospecimen donors who expressed a preference (62 of 83 donors; 75%) wanted their biological materials transferred to another biobank, specifically an academic bank or a national bank. The most unacceptable options for the handling of tissue were transfer to a for-profit/pharmaceutical biobank (39 of 98 donors; 40%) or a biobank based outside of the United States (31 of 98 donors; 32%). Nonwhite participants were more likely to view the transfer of their tissue to a for-profit/pharmaceutical tissue bank, international tissue bank, or a national tissue bank as unacceptable compared with white participants.

conclusionsAccording to these biospecimen donors, the most acceptable options for the handling of biospecimens after biobank closure were transfer to an academic or national bank. The most objectionable options were transfer to a for-profit/pharmaceutical biobank or a biobank based outside of the United States. These findings can be used as the basis for educational interventions directed at the public and can inform the policies of biobanks that serve oncology research. Cancer 2017;123:4648-4652. © 2017 American Cancer Society.

Indexed as

Patient PreferenceSpecimen HandlingAcademies and InstitutesBiological Specimen BanksBiomedical ResearchFemaleHumansMaleMiddle AgedTissue DonorsUnited Statesresearchtissue banktissue bank closuretissue donationtissue donor perspectives

Identifiers

PMID28746751
PMCPMC5693705
OpenAlexW2738085505

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.