ArticleArquivos brasileiros de cardiologia2017
Single Derivation Fragmented QRS Can Predict Poor Prognosis in Successfully Revascularized Acute STEMI Patients.
Article in Arquivos brasileiros de cardiologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- The Predictive Value of Fragmented QRS for Cardiovascular Events in Acute Myocardial Infarction: A Systematic Review and Meta-Analysis.Frontiers in physiology · 2020Pooled it
- Fragmented QRS as a Marker of Myocardial Fibrosis in Hypertension: a Systematic Review.Current hypertension reports · 2019Pooled it
- Fragmented QRS and mortality in patients undergoing percutaneous intervention for ST-elevation myocardial infarction: Systematic review and meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Pooled it
- Application Value of QRS Wave Potential in Predicting Left Ventricular Remodeling and Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction After PCI.International journal of general medicine · 2026Article
- Risk Factors for QRS-Fragmentation in Patients with STEMI Undergoing PCI.Medicina (Kaunas, Lithuania) · 2025Article
- Relationship between Fragmented QRS and Microvascular Dysfunction in Masked Hypertension.Pulse (Basel, Switzerland) · 2022Article
- The relationship between myocardial bridge and frontal QRS-T angle.Journal of arrhythmia · 2022Article
- The Association Between Qtc, Qtd, TPE, And Fragmented QRS Before And After PPCI With Hospital Mortality In STEMI Patients.Cardiovascular & hematological disorders drug targets · 2022Article
- Characteristics of Circadian Blood Pressure Pattern of Hypertensive Patients According to Localization of Fragmented QRS on Electrocardiography.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Association Between Non-Dipping and Fragmented QRS Complexes in Prehypertensive Patients.Arquivos brasileiros de cardiologia · 2019Article
- Combining fragmented QRS and TIMI score for predicting in-hospital short-term prognosis after acute myocardial infarction.Journal of Zhejiang University. Science. B · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQRS fragmentation (fQRS) is classically defined as the presence of slurred QRS morphology in at least two contiguous leads, and its prognostic importance has been shown in ST elevation myocardial infarction (STEMI). However, no study has investigated the significance of single lead fQRS (sl-fQRS) in surface electrocardiography (ECG).
objectivesTo evaluate whether sl-fQRS is as valuable as classical fQRS in patients with acute STEMI who had successful revascularization with primary percutaneous coronary intervention (pPCI).
methodsWe included 330 patients with a first STEMI who had been successfully revascularized with pPCI. The patient's electrocardiography was obtained in the first 48 hours, and the patients were divided into three groups according to the absence of fQRS (no-fQRS); fQRS presence in a single lead (sl-fQRS); and ≥2 leads with fQRS (classical fQRS).
resultsIn-hospital mortality was significantly higher both in patients with sl-fQRS and in patients with ≥ 2 leads with fQRS compared to patients with no-fQRS. In ROC curve analysis, ≥ 1 leads with fQRS yielded a sensitivity of 75% and specificity of 57.4% for the prediction of in-hospital mortality. Multivariate analysis showed that sl-fQRS is an independent predictor of in-hospital mortality (OR: 3.989, 95% CI: 1.237-12.869, p = 0.021).
conclusionsAlthough the concept of at least two derivations is mentioned for the classical definition of fQRS, our study showed that fQRS in only one lead is also associated with poor outcomes. Therefore, ≥1 leads with fQRS can be useful when describing the patients under high cardiac risk in acute STEMI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.