Evidence map›Paper›PMID 28746372›Full record

ArticlePLoS medicine2017

Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines.

Emilie Alirol, Teodora E Wi, Manju Bala, Maria Luiza Bazzo, Xiang-Sheng Chen, Carolyn Deal, Jo-Anne R Dillon, Ranmini Kularatne, Jutta Heim, Rob Hooft van Huijsduijnen and 9 more

Abstract read
In one paragraph

Article in PLoS medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

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  4. Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Trial
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Emilie AlirolGlobal Antibiotics Research and Development Partnership (GARDP), Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.ORCID http://orcid.org/0000-0001-8691-3991
Teodora E WiWorld Health Organization (WHO), Geneva, Switzerland.ORCID http://orcid.org/0000-0002-7640-9166
Manju BalaRegional STD Teaching, Training & Research Centre, VMMC and Safdarjung Hospital, New Delhi, India.
Maria Luiza BazzoFederal University of Santa Catarina, Florianópolis, Brazil.
Xiang-Sheng ChenNational Center for STD Control, Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Dermatology, Nanjing, China.
Carolyn DealSTD Branch, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), Rockville, Maryland, United States of America.
Jo-Anne R DillonUniversity of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Ranmini KularatneCentre for HIV & Sexually Transmitted Infections, National Institute for Communicable Diseases, Johannesburg, South Africa.
Jutta HeimGlobal Antibiotics Research and Development Partnership (GARDP), Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Rob Hooft van HuijsduijnenGlobal Antibiotics Research and Development Partnership (GARDP), Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.ORCID http://orcid.org/0000-0002-2261-9424
Edward W HookUniversity of Alabama, Birmingham, Alabama, United States of America.
Monica M LahraWorld Health Organization Collaborating Centre for Sexually Transmitted Diseases, South Eastern Area Laboratory Services, The Prince of Wales Hospital, Sydney, Australia.
David A LewisWestern Sydney Sexual Health Centre, Parramatta, NSW, Australia, and Marie Bashir Institute for Infectious Diseases and Biosecurity & Sydney Medical School-Westmead, University of Sydney, Westmead, Australia.
Francis NdowaSkin & GU Medicine Clinic, Harare, Zimbabwe.
William M ShaferDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America, and Laboratories of Bacterial Pathogenesis, VA Medical Center, Decatur, Georgia, United States of America.
Liz TaylerWorld Health Organization (WHO), Geneva, Switzerland.ORCID http://orcid.org/0000-0001-7533-613X
Kimberly WorkowskiDepartment of Medicine, Division of Infectious Diseases, Emory University, Atlanta, Georgia, United States of America.ORCID http://orcid.org/0000-0002-9918-9493
Magnus UnemoWorld Health Organization Collaborating Centre for Gonorrhoea and other STIs, Örebro University, Örebro, Sweden.
Manica BalasegaramGlobal Antibiotics Research and Development Partnership (GARDP), Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.ORCID http://orcid.org/0000-0002-2091-6660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emilie Alirol and colleagues discuss the development of new treatments for gonorrhea.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsGonorrheaNeisseria gonorrhoeaeResearchAnti-Bacterial Agents

Identifiers

PMID28746372
PMCPMC5528252

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.