Evidence map›Paper›PMID 28746229›Full record

ArticleMedicine2017

The prognostic value of preoperative inflammation-based prognostic scores and nutritional status for overall survival in resected patients with nonmetastatic Siewert type II/III adenocarcinoma of esophagogastric junction.

Lixiang Zhang, Yezhou Su, Zhangming Chen, Zhijian Wei, Wenxiu Han, Aman Xu

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Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

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25citing papers in PubMed, 5 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  9. Impact of preoperative prealbumin levels on long-term prognosis in patients with gastric cancer after gastrectomy: a retrospective cohort study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Lixiang ZhangDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Anhui Medical University Anhui Medical University, Hefei, Anhui, China.
Yezhou Su
Zhangming Chen
Zhijian Wei
Wenxiu Han
Aman Xu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune and nutritional status of patients have been reported to predict postoperative complications, recurrence, and prognosis of patients with cancer. Therefore, this retrospective study aimed to explore the prognostic value of preoperative inflammation-based prognostic scores [neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR)] and nutritional status [prognostic nutritional index (PNI), body mass index (BMI), hemoglobin, albumin, and prealbumin] for overall survival (OS) in adenocarcinoma of esophagogastric junction (AEG) patients.

methodsA total of 355 patients diagnosed with Siewert type II/III AEG and underwent surgery between October 2010 and December 2011 were followed up until October 2016. Receiver operating characteristic (ROC) curve analysis was used to determine the cutoff values of NLR, PLR, and PNI. Kaplan-Meier curves and Cox regression analyses were used to calculate the OS characteristics.

resultsThe ideal cutoff values for predicting OS were 3.5 for NLR, 171 for PLR, and 51.3 for PNI according to the ROC curve. The patients with hemoglobin <120 g/L (P = .001), prealbumin <180 mg/L (P = .000), PNI <51.3 (P = .010), NLR >3.5 (P = .000), PLR >171 (P = .006), and low BMI group (P = .000) had shorter OS. And multivariate survival analysis using the Cox proportional hazards model showed that the tumor-node-metastasis stage, BMI, NLR, and prealbumin levels were independent risk factors for the OS.

conclusionOur study demonstrated that preoperative prealbumin, BMI, and NLR were independent prognostic factors of AEG patients.

Indexed as

Nutritional StatusAdenocarcinomaAdultAgedAged, 80 and overArea Under CurveBiomarkers, TumorBody Mass IndexEsophageal NeoplasmsEsophagogastric JunctionFemaleFollow-Up StudiesHumansKaplan-Meier EstimateLymphocyte CountMaleBiomarkers, TumorPrealbumin

Identifiers

PMID28746229
PMCPMC5627855

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.