Trial reportMedicine2017
Alveolar recruitment maneuver attenuates extravascular lung water in acute respiratory distress syndrome.
Trial report in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05023226 (Effectiveness of Recruitment Maneuvers and Lung Protective Ventilation Strategy in ARDS), which is not on this map. Cited by 10 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Recruitment Maneuvers and Lung Protective Ventilation Strategy in ARDS
Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Recruitment maneuvers in patients with acute respiratory distress syndrome: a systematic review and metanalysis.Einstein (Sao Paulo, Brazil) · 2024Pooled it
- Association of Positive End-Expiratory Pressure and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-analysis.American journal of respiratory and critical care medicine · 2022Pooled it
- Impact of differences in acute respiratory distress syndrome randomised controlled trial inclusion and exclusion criteria: systematic review and meta-analysis.British journal of anaesthesia · 2021Pooled it
- Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation: a systematic review and meta-analysis.Journal of critical care · 2019Pooled it
- Saudi Guideline for Mechanical Ventilation in Adults.Saudi journal of medicine & medical sciences · 2026Article
- Positive end-expiratory pressure titration in acute respiratory distress syndrome-a practical bedside algorithm.Frontiers in medicine · 2026Review
- Open lung ventilation with low tidal volumes, staircase recruitment maneuvers, high PEEP and decremental PEEP titration vs ARDSNet in ARDS: A systematic review and meta-analysis.Journal of anesthesia and translational medicine · 2025Review
- ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies.Intensive care medicine · 2023Article
- ARDS Clinical Practice Guideline 2021.Journal of intensive care · 2022Article
- Extravascular lung water measurements in acute respiratory distress syndrome: why, how, and when?Current opinion in critical care · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe alveolar recruitment maneuver (RM) has been reported to improve oxygenation in acute respiratory distress syndrome (ARDS) and may be related to reduced extravascular lung water (EVLW) in animals. This study was designed to investigate the effects of RM on EVLW in patients with ARDS.
methodsAn open label, prospective, randomized controlled trial including patients with ARDS was conducted in hospitals in North Taiwan between 2010 and 2016. The patients were divided into 2 groups (with and without RM). The primary endpoint was the comparison of the EVLW index between the 2 groups.
resultsTwenty-four patients with ARDS on mechanical ventilator support were randomized to receive ventilator treatment with RM (RM group, n = 12) or without RM (non-RM group, n = 12). Baseline demographic characteristics were similar between the 2 groups. After recruitment, the day 3 extravascular lung water index (EVLWI) (25.3 ± 9.3 vs 15.5 ± 7.3 mL/kg, P = .008) and the arterial oxygen tension/fractional inspired oxygen ratio (PaO2/FiO2) (132.3 ± 43.5 vs 185.6 ± 38.8 mL/kg, P = .003) both improved over that of day 1. However, both EVLWI and PaO2/FiO2 did not significantly change from day 1 to 3 in the non-RM group.
conclusionRM is a feasible method for improving oxygenation and the EVLW index in patients with ARDS, as well as for decreasing ventilator days and intensive care unit stay duration.
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