ArticleMedicine2017
Correlation between high-intensity zone on MRI and discography in patients with low back pain.
Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Does the high-intensity zone of lumbar intervertebral disc at magnetic resonance imaging have diagnostic value for discogenic low back pain? A meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- The correlation between the lumbar disc MRI high-intensity zone and discogenic low back pain: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- The Sinuvertebral Nerve and Basivertebral Nerve: Analyzing the Central Role of the Vertebral-Disc Unit in Chronic Low Back Pain.Current pain and headache reports · 2026Review
- High-intensity zones in dogs with lumbosacral intervertebral disc degeneration: insights from MRI and histopathological findings.The veterinary quarterly · 2025Article
- Comparison of magnetic resonance imaging findings among sciatica patients classified as centralizers or non-centralizers.The Journal of manual & manipulative therapy · 2023Article
- Article
- Predictors of discogenic pain in magnetic resonance imaging: a retrospective study of provocative discography performed by posterolateral approach.The Korean journal of pain · 2021Article
- Intradiscal quantitative chemical exchange saturation transfer MRI signal correlates with discogenic pain in human patients.Scientific reports · 2021Observational
- Factors Predicting the Clinical Outcome After Trans-sacral Epiduroscopic Laser Decompression for Lumbar Disc Herniation.Neurospine · 2021Article
- Imaging Analysis of the High-Intensity Zone on Lumbar Spine Magnetic Resonance Images: Classification, Features and Correlation with Low Back Pain.Journal of pain research · 2021Article
- Factors associated with lumbar disc high-intensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients.Journal of orthopaedic surgery and research · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to analyze the correlation between high-intensity zone (HIZ) on magnetic resonance imaging (MRI) of a lumbar disc and positive pain response assessed by discography for the diagnosis and treatment of discogenic low back pain (LBP). Thirty-seven patients aged 21 to 59 years with chronic LBP but without any neurological symptoms or lumbar disc herniation who underwent MRI and subsequent discography were included in this study. During discography, concordant pain was regarded as positive, whereas discordant pain and no pain were regarded as negative. X-ray and computed tomography (CT) after discography with positive pain response were analyzed to correlate with HIZ on MRI. A total of 98 discs underwent discography in 37 patients; 21 discs presented positive pain response, including 10 with HIZ (47.6%). Seventy-seven discs presented negative pain response, including 29 with HIZ (37.6%). The high grade of annular disruption group shows a high proportion of HIZ on MRI. A positive correlation between HIZ and degree of annular disruption was observed. However, no correlation between HIZ and positive pain response was established on discography. The findings confirm that the presence of HIZ on MRI is only a suggestive and screening iconography indication for the diagnosis of discogenic LBP and cannot replace the gold standard of the discography. MRI should be closely integrated with those of discography, and thus, they play a crucial role in selecting operative segments of multilevel lumbar degenerative disk disease.
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