Evidence map›Paper›PMID 28745646›Full record

ArticleJournal of visualized experiments : JoVE2017

Reducing State Anxiety Using Working Memory Maintenance.

Nicholas L Balderston, Abigail Hsiung, Jeffrey Liu, Monique Ernst, Christian Grillon

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas L BalderstonSection on Neurobiology of Fear and Anxiety, National Institute of Mental Health, National Institutes of Health (NIH); Nicholas.balderston@nih.gov.
Abigail HsiungSection on Neurobiology of Fear and Anxiety, National Institute of Mental Health, National Institutes of Health (NIH).
Jeffrey LiuSection on Neurobiology of Fear and Anxiety, National Institute of Mental Health, National Institutes of Health (NIH).
Monique ErnstSection on Neurobiology of Fear and Anxiety, National Institute of Mental Health, National Institutes of Health (NIH).
Christian GrillonSection on Neurobiology of Fear and Anxiety, National Institute of Mental Health, National Institutes of Health (NIH).

Funding

The Psychophysiology Of Fear And AnxietyZIAMH002798 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI GRILLON, CHRISTIAN · 2009 to 2022
$29.0M
Intramural NIH HHS ZIA MH002798
6 · The paper itself

Abstract

The purpose of this protocol is to explain how to examine the relationship between working memory processes and anxiety by combining the Sternberg Working Memory (WM) and the threat of shock paradigms. In the Sternberg WM paradigm, subjects are required to maintain a series of letters in the WM for a brief interval and respond by identifying whether the position of a given letter in the series matches a numerical prompt. In the threat of shock paradigm, subjects are exposed to alternating blocks where they are either at risk of receiving unpredictable presentations of a mild electric shock or are safe from the shock. Anxiety is probed throughout the safe and threat blocks using the acoustic startle reflex, which is potentiated under threat (Anxiety-Potentiated Startle (APS)). By conducting the Sternberg WM paradigm during the threat of shock and probing the startle response during either the WM maintenance interval or the intertrial interval, it is possible to determine the effect of WM maintenance on APS.

Indexed as

AnxietyFearFemaleHumansMaleMemory, Short-TermReflex, Startle

Identifiers

PMID28745646
PMCPMC5612581

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.