ArticleeLife2017
The heritability of multi-modal connectivity in human brain activity.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of neuroimaging epigenetic research: calling for an increased focus on development.Molecular psychiatry · 2023Pooled it
- Individualized Network Topography in Pre-adolescent Children and Adults Using Naturalistic Precision fMRI.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Age-Related Changes in Spontaneous Brain Dynamics Revealed by Resting-State Magnetoencephalography.GeroScience · 2026Article
- Exploration of Genetic Overlap of Brain Phenotypes With Schizophrenia: Different Methods Provide Complementary Insights.Schizophrenia bulletin · 2026Article
- Article
- The role of white matter myelin in structural-functional network coupling.Communications biology · 2026Article
- Unsupervised Representation Learning Generates Differentiable Neurophysiological Profiles.bioRxiv : the preprint server for biology · 2026Article
- Article
- Phenome-wide analysis of genetically imputed neuroimaging phenotypes reveals associations with psychiatric traits in a multi-ancestry cohort.medRxiv : the preprint server for health sciences · 2025Article
- Familial transmission of neural representations for mental arithmetic across two generations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genetic fingerprinting with heritable phenotypes of the resting-state brain network topology.Communications biology · 2024Article
- A ventromedial visual cortical 'Where' stream to the human hippocampus for spatial scenes revealed with magnetoencephalography.Communications biology · 2024Article
- Heart-Brain Axis: A Narrative Review of the Interaction between Depression and Arrhythmia.Biomedicines · 2024Review
- Multi-organ imaging-derived polygenic indexes for brain and body health.medRxiv : the preprint server for health sciences · 2024Article
- Two common and distinct forms of variation in human functional brain networks.Nature neuroscience · 2024Article
- Dissociation of Reliability, Heritability, and Predictivity in Coarse- and Fine-Scale Functional Connectomes during Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Human Sensorimotor Beta Event Characteristics and Aperiodic Signal Are Highly Heritable.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Rapid dynamics of electrophysiological connectome states are heritable.bioRxiv : the preprint server for biology · 2024Article
- Rapid dynamics of electrophysiological connectome states are heritable.Network neuroscience (Cambridge, Mass.) · 2024Article
- Discovering individual fingerprints in resting-state functional connectivity using deep neural networks.Human brain mapping · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Patterns of intrinsic human brain activity exhibit a profile of functional connectivity that is associated with behaviour and cognitive performance, and deteriorates with disease. This paper investigates the relative importance of genetic factors and the common environment between twins in determining this functional connectivity profile. Using functional magnetic resonance imaging (fMRI) on 820 subjects from the Human Connectome Project, and magnetoencephalographic (MEG) recordings from a subset, the heritability of connectivity among 39 cortical regions was estimated. On average over all connections, genes account for about 15% of the observed variance in fMRI connectivity (and about 10% in alpha-band and 20% in beta-band oscillatory power synchronisation), which substantially exceeds the contribution from the environment shared between twins. Therefore, insofar as twins share a common upbringing, it appears that genes, rather than the developmental environment, have the dominant role in determining the coupling of neuronal activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.