ReviewArchives of pathology & laboratory medicine2017
Soft Tissue Tumor Immunohistochemistry Update: Illustrative Examples of Diagnostic Pearls to Avoid Pitfalls.
Review in Archives of pathology & laboratory medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 96 citations in OpenAlex.
- Primary synovial sarcoma of the thyroid mimicking medullary thyroid cancer.JCEM case reports · 2026Article
- Giant Retroperitoneal Liposarcoma Without Organ Invasion: A Rare Case Report.The American journal of case reports · 2026Article
- Case Report: Synaptophysin-positive SMARCA4-deficient undifferentiated thoracic tumour: a diagnostic pitfall with therapeutic implications.Frontiers in oncology · 2026Article
- Refractory Orbital Spindle Cell Carcinoma With Rapid Progression and Intracranial Extension.Case reports in ophthalmological medicine · 2026Article
- Bronchial artery embolization followed by bronchoscopic electrosurgical snare resection for diagnosis and treatment of primary pulmonary osteosarcoma: case report and literature review.Frontiers in medicine · 2026Article
- Histomorphological and molecular characteristics of liposarcoma (Review).Oncology letters · 2025Review
- Clinicopathological Study of Soft Tissue Neoplasms.Cureus · 2025Article
- Clinicopathological Spectrum of Myxoid Soft Tissue Tumours with Emphasis on Diagnostic Differentials.Sultan Qaboos University medical journal · 2025Article
- A practical risk stratification system based on ultrasonography and clinical characteristics for predicting the malignancy of soft tissue masses.Insights into imaging · 2024Article
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- Exploring Solitary Fibrous Tumors at a Tertiary Cancer Center: Clinicopathological and Immunomorphologic Profile.Cureus · 2024Article
- Cardiac Magnetic Resonance to Predict Cardiac Mass Malignancy: The CMR Mass Score.Circulation. Cardiovascular imaging · 2024Observational
- Article
- Primary well differentiated hepatic liposarcoma in a meerkat (Suricata suricatta).The Journal of veterinary medical science · 2023Article
- Analysis on diagnostic failure of US-guided core needle biopsy for soft tissue tumors.Research in diagnostic and interventional imaging · 2023Article
- Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia.Case reports in radiology · 2023Article
- Giant retroperitoneal liposarcoma measuring 27 × 29 × 36 cm: a case report.Journal of surgical case reports · 2023Article
- Investigating the role of signal transducer and activator of transcription 3 in feline injection site sarcoma.BMC veterinary research · 2022Article
- Spindle cell lesions of the breast: a diagnostic approach.Virchows Archiv : an international journal of pathology · 2022Review
- Spindle Cell Squamous Cell Carcinoma of Head and Neck Region: a Clinicopathological and Immunohistochemical Study.Indian journal of surgical oncology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
context- Current 2013 World Health Organization classification of tumors of soft tissue arranges these tumors into 12 groups according to their histogenesis. Tumor behavior is classified as benign, intermediate (locally aggressive), intermediate (rarely metastasizing), and malignant. In our practice, a general approach to reaching a definitive diagnosis of soft tissue tumors is to first evaluate clinicoradiologic, histomorphologic, and cytomorphologic features of the tumor to generate some pertinent differential diagnoses. These include the potential line of histogenesis and whether the tumor is benign or malignant, and low or high grade. Although molecular/genetic testing is increasingly finding its applications in characterizing soft tissue tumors, currently immunohistochemistry still not only plays an indispensable role in defining tumor histogenesis, but also serves as a surrogate for underlining molecular/genetic alterations. Objective- To provide an overview focusing on the current concepts in the classification and diagnosis of soft tissue tumors, incorporating immunohistochemistry. This article uses examples to discuss how to use the traditional and new immunohistochemical markers for the diagnosis of soft tissue tumors. Practical diagnostic pearls, summary tables, and figures are used to show how to avoid diagnostic pitfalls. DATA SOURCES: - Data were obtained from pertinent peer-reviewed English-language literature and the authors' first-hand experience as bone and soft tissue pathologists.
conclusions- -The ultimate goal for a pathologist is to render a specific diagnosis that provides diagnostic, prognostic, and therapeutic information to guide patient care. Immunohistochemistry is integral to the diagnosis and management of soft tissue tumors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.