Evidence map›Paper›PMID 28745403›Full record

ArticleThe British journal of surgery2017

Sex differences in mortality after abdominal aortic aneurysm repair in the UK.

D A Sidloff, A Saratzis, M J Sweeting, J Michaels, J T Powell, S G Thompson, M J Bown

Open access · bronzeAbstract read
In one paragraph

Article in The British journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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  14. Studies Related to Ruptured Abdominal Aortic Aneurysms in the Past 10 Years (2011-2020): A Bibliometric Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

D A SidloffVascular Surgery Group, Department of Cardiovascular Sciences and National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK.
A SaratzisVascular Surgery Group, Department of Cardiovascular Sciences and National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK.
M J SweetingDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
J MichaelsHealth Economics and Decision Science, University of Sheffield, Sheffield, UK.
J T PowellVascular Surgery Research Group, Imperial College, London, UK.
S G ThompsonDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
M J BownVascular Surgery Group, Department of Cardiovascular Sciences and National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK.
National Institute for Health Research · GBUniversity of Cambridge · GBImperial College London · GBNIHR Leicester Cardiovascular Biomedical Research Unit · GBUniversity of Sheffield · GB

Funding

British Heart Foundation RG/08/014/24067Department of Health HTA/14/179/01Department of Health RP-PG-1210-12009Medical Research Council MR/L003120/1
6 · The paper itself

Abstract

backgroundThe UK abdominal aortic aneurysm (AAA) screening programmes currently invite only men for screening because the benefit in women is uncertain. Perioperative risk is critical in determining the effectiveness of screening, and contemporary estimates of these risks in women are lacking. The aim of this study was to compare mortality following AAA repair between women and men in the UK.

methodsAnonymized data from the UK National Vascular Registry (NVR) for patients undergoing AAA repair (January 2010 to December 2014) were analysed. Co-variables were extracted for analysis by sex. The primary outcome measure was in-hospital mortality. Secondary outcome measures included mortality by 5-year age groups and duration of hospital stay. Logistic regression was performed to adjust for age, calendar time, AAA diameter and smoking status. NVR-based outcomes were checked against Hospital Episode Statistics (HES) data.

resultsA total of 23 245 patients were included (13·0 per cent women). Proportionally, more women than men underwent open repair. For elective open AAA repair, the in-hospital mortality rate was 6·9 per cent in women and 4·0 per cent in men (odds ratio (OR) 1·48, 95 per cent c.i. 1·08 to 2·02; P = 0·014), whereas for elective endovascular AAA repair it was 1·8 per cent in women and 0·7 per cent in men (OR 2·86, 1·72 to 4·74; P < 0·001); the results in HES were similar. For ruptured AAA, there was no sex difference in mortality within the NVR; however, in HES, for ruptured open AAA repair, the in-hospital mortality rate was higher in women (33·6 versus 27·1 per cent; OR 1·36, 1·16 to 1·59; P < 0·001).

conclusionWomen have a higher in-hospital mortality rate than men after elective AAA repair even after adjustment. This higher mortality may have an impact on the benefit offered by any screening programme offered to women.

Indexed as

Hospital MortalityAge FactorsAortic Aneurysm, AbdominalAortic RuptureElective Surgical ProceduresEndovascular ProceduresFemaleHumansLength of StayMaleRegistriesUnited Kingdom

Identifiers

PMID28745403
PMCPMC5655705
OpenAlexW2739366509

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.