Evidence map›Paper›PMID 28745385›Full record

ArticleJournal of biomedical optics2017

Multiview Hilbert transformation in full-ring transducer array-based photoacoustic computed tomography.

Lei Li, Liren Zhu, Yuecheng Shen, Lihong V Wang

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  3. Review
  4. All-opticalPhotoacoustics · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei LiWashington University in St. Louis, Department of Electrical and System Engineering, St. Louis, Missouri, United StatesbCalifornia Institute of Technology, Andrew and Peggy Cherng Department of Medical Engineering, Caltech Optical Imaging Laboratory, Pasadena, California, United States.
Liren ZhuCalifornia Institute of Technology, Andrew and Peggy Cherng Department of Medical Engineering, Caltech Optical Imaging Laboratory, Pasadena, California, United StatescWashington University in St. Louis, Department of Biomedical Engineering, St. Louis, Missouri, United States.
Yuecheng ShenCalifornia Institute of Technology, Andrew and Peggy Cherng Department of Medical Engineering, Caltech Optical Imaging Laboratory, Pasadena, California, United States.
Lihong V WangCalifornia Institute of Technology, Andrew and Peggy Cherng Department of Medical Engineering, Caltech Optical Imaging Laboratory, Pasadena, California, United StatesdCalifornia Institute of Technology, Department of Electrical Engineering, Caltech Optical Imaging Laboratory, Pasadena, California, United States.

Funding

PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
IN VIVO IMAGING OF SINGLE CIRCULATING CELLSR01CA186567 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2013 to 2017
$3.6M
Deep brain photoacoustic tomography at single-neuron resolution using arrays of photonic emitters and high-frequency ultrasound transducersU01NS099717 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ROUKES, MICHAEL L, SHEPARD, KENNETH L · 2016 to 2018
$3.0M
FAST HIGH-RESOLUTION DEEP PHOTOACOUSTIC TOMOGRAPHY OF ACTION POTENTIALS IN BRAINSU01NS090579 · NINDS · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2014 to 2016
$2.7M
WHOLE-BODY SMALL-ANIMAL PHOTOACOUSTIC-ULTRASONIC COMPUTED TOMOGRAPHYR01EB016963 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2013 to 2016
$2.4M
NCI NIH HHS R01 CA186567NIBIB NIH HHS DP1 EB016986NIBIB NIH HHS R01 EB016963NINDS NIH HHS U01 NS090579NINDS NIH HHS U01 NS099717
6 · The paper itself

Abstract

Based on the photoacoustic (PA) effect, PA tomography directly measures specific optical absorption, i.e., absorbed optical energy per unit volume. We recently developed a full-ring ultrasonic transducer array-based photoacoustic computed tomography (PACT) system for small-animal whole-body imaging. The system has a full-view detection angle and high in-plane resolution (∼100  μm). However, due to the bandpass frequency response of the piezoelectric transducer elements and the limited elevational detection coverage of the full-ring transducer array, the reconstructed images present bipolar (i.e., both positive and negative) pixel values, which cause ambiguities in image interpretation for physicians and biologists. We propose a multiview Hilbert transformation method to recover the unipolar initial pressure for full-ring PACT. The effectiveness of the proposed algorithm was first validated by numerical simulations and then demonstrated with ex vivo mouse brain structural imaging and in vivo mouse whole-body imaging.

Indexed as

Tomography, X-Ray ComputedAlgorithmsAnimalsMicePhotoacoustic TechniquesTransducersWhole Body Imaging

Identifiers

PMID28745385
PMCPMC5527266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.