Evidence map›Paper›PMID 28744832›Full record

ArticleProbiotics and antimicrobial proteins2018

Isolation and Selection of Potential Probiotic Bacteria from the Pig Gastrointestinal Tract.

Luca Lo Verso, Martin Lessard, Guylaine Talbot, Benoit Fernandez, Ismail Fliss

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Targeting Enterococci with Antimicrobial Activity againstAntibiotics (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Screening of Bacteria InhibitingMicroorganisms · 2022
    Article
  10. Bacteriocins: Properties and potential use as antimicrobials.Journal of clinical laboratory analysis · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Dual Inhibition ofMicroorganisms · 2021
    Article
  18. Selection of ImmunobioticMicroorganisms · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Luca Lo VersoSherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, 2000 College Street, Sherbrooke, Quebec, J1M 0C8, Canada. luca.loverso@agr.gc.ca.ORCID 0000-0003-0925-8107
Martin LessardSherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, 2000 College Street, Sherbrooke, Quebec, J1M 0C8, Canada.
Guylaine TalbotSherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, 2000 College Street, Sherbrooke, Quebec, J1M 0C8, Canada.
Benoit FernandezInstitute of Nutrition and Functional Foods, Université Laval, Quebec City, Quebec, G1K 7P4, Canada.
Ismail FlissInstitute of Nutrition and Functional Foods, Université Laval, Quebec City, Quebec, G1K 7P4, Canada.
Agriculture and Agri-Food Canada · CAUniversité Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to isolate bacterial strains from the pig gastrointestinal tract that have antagonistic activity against potential pathogens and are able to produce antimicrobial compounds. That ability would be a first requirement for the strains' possible use as probiotics. Samples obtained from pig intestinal mucosa and contents were screened for the presence of antagonistic activity against pathogenic indicator strains of Escherichia coli, Salmonella, and Listeria by means of the double-layer technique. Samples displaying the largest inhibitory halos were further studied for the production of inhibitory substances using the agar diffusion and microtitration methods. The three most promising isolates were identified by sequencing of the 16S rRNA gene and showed highest affiliation to Lactobacillus salivarius. Optimal growth conditions and bacteriocin production were recorded in de Man, Rogosa, and Sharpe broth under anaerobic conditions at 37 °C. The antimicrobial substances were found to be sensitive to proteolytic enzymes but showed good stability at pH values below 6. Our findings suggest that these three intestinal strains are able to produce antimicrobial substances capable of inhibiting the growth of potential enteric pathogens and might have potential as probiotic feed additives for the prevention of gastrointestinal diseases.

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaBacteriocinsGastrointestinal TractProbioticsSwineAnti-Bacterial AgentsBacteriocinsAntagonistic activityLactobacillusPorcine gastrointestinal tractProbiotic

Identifiers

PMID28744832
OpenAlexW2738328393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.