Observational studyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2017
Affective symptoms and determinants of health-related quality of life in Mexican people with epilepsy.
Observational study in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Co-morbid mental health conditions in people with epilepsy and association with quality of life in low- and middle-income countries: a systematic review and meta-analysis.Health and quality of life outcomes · 2023Pooled it
- Medication adherence in epilepsy: Validation of the short medication adherence scale (SMAS-7) and mediation analysis of quality-of-life pathways.Exploratory research in clinical and social pharmacy · 2026Article
- Quality of Life Among Patients With Epilepsy in Jeddah, Saudi Arabia: A Descriptive Cross-Sectional Study.Nursing research and practice · 2026Article
- Anxiety and depression symptoms mediate the impact of neuroticism on insomnia in adults with epilepsy: a cross-sectional study.BMC neurology · 2025Article
- Patient complexity, depression, and quality of life in patients with epilepsy at an epilepsy center in Japan.Epilepsia open · 2022Observational
- Effects of insomnia and levels of depression and anxiety symptoms on quality of life in people with epilepsy.BMC psychiatry · 2022Article
- QUALITY OF LIFE IN PATIENTS WITH EPILEPSY - SINGLE CENTRE EXPERIENCE.Acta clinica Croatica · 2021Article
- Quality of life among epileptic patients in Qassim Region, KSA.Neurosciences (Riyadh, Saudi Arabia) · 2021Article
- Prevalence of insomnia symptoms and their associated factors in patients treated in outpatient clinics of four general hospitals in Guangzhou, China.BMC psychiatry · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy is known to be associated with multiple psychiatric comorbidities, such as depression, sleep-disorders, and anxiety. The objective of this study was to determine the prevalence and impact of affective symptoms over health-related quality of life (QOL) in Mexican people with epilepsy (PWE). We performed a cross-sectional observational study on 73 consecutive PWE and corresponding age- and sex-matched controls. HrQOL was assessed using the QOLIE-10 (QOL in Epilepsy-10) instrument. Clinical and demographic characteristics were recorded, and instruments evaluating depressive/anxiety symptoms, sleep quality, and insomnia were completed. PWE had more depressive/anxiety symptoms when compared with controls. QOLIE-10 scores were significantly inversely correlated with poor sleep quality, insomnia symptoms, depressive/anxiety symptoms, and number of anti-epileptic drugs used, but not with seizure type or number of seizures per month. A poor QOL was independently associated only with anti-epileptic drug polytherapy. PWE are burdened with depressive/anxiety symptoms at alarming rates. The presence of depressive symptoms along with sleep disturbances and more significantly, anti-epileptic drug polytherapy, appears to negatively impact QOL, to a greater degree than short-term seizure control.
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