ArticleOpen medicine (Warsaw, Poland)2017
Pathophysiology of Meningioma Growth in Pregnancy.
Article in Open medicine (Warsaw, Poland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 70 citations in OpenAlex.
- Genomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas.Neuro-oncology · 2026Article
- Intrasellar meningioma versus pituitary apoplexy in the setting of postpartum hemorrhage: a case report.BMC pregnancy and childbirth · 2026Article
- Case report: Congenital Bednar tumor with pregnancy-associated growth and pain: a diagnostic pitfall with blue nevus-like features.Frontiers in oncology · 2026Article
- Brain Tumors in Pregnancy: A Review of Pathophysiology, Clinical Management, and Ethical Dilemmas.Cancers · 2025Review
- Article
- Management of an intracranial meningioma in pregnancy in low resource setting: A case report and literature review.International journal of surgery case reports · 2025Article
- The Molecular and Cellular Basis of Physiological Changes in Pregnancy and Its Implications in Neurologic and Ophthalmic Pathologies.International journal of molecular sciences · 2025Review
- Simultaneous surgical management of a giant tuberculum sellae meningioma and pregnancy-related complications: a case report and literature review.Frontiers in oncology · 2025Article
- Intraoperative neuromonitoring of visual evoked potentials in a pregnant patient with meningioma: a case report.BMC neurology · 2024Article
- A Narrative Review on Neuro-Ophthalmological Manifestations That May Occur during Pregnancy.Life (Basel, Switzerland) · 2024Review
- Meningioma Prognostic Tool Based on Correlation of Histopathological Grading and Immunohistochemistry.Oman medical journal · 2024Article
- Vertigo During Pregnancy: A Narrative Review of the Etiology, Pathophysiology, and Treatment.Cureus · 2024Review
- Meningioma in the third trimester of pregnancy: A case report.Case reports in women's health · 2023Article
- Review
- Neurosurgical emergencies during pregnancy - Management dilemmas.Surgical neurology international · 2023Article
- Intradural extramedullary spinal cord meningioma with a rare extradural foraminal extension: A case report.Frontiers in surgery · 2023Article
- Review
- Expressions of Progesterone Receptor of Orbital Meningiomas in Indonesia.Asian Pacific journal of cancer prevention : APJCP · 2022Observational
- Pregnancy and Childbirth in Women With Meningioma.Cureus · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meningioma is among the most frequent brain tumours predominantly affecting elderly women. Epidemiological studies have shown that at the age of fertility the incidence is relatively low. The biological behaviour of meningioma in pregnancy is different from other meningiomas. The possible explanation is rooted in the complex physiological changes and hormonal differences during pregnancy. The increased meningioma growth observed in pregnancy is presumably the result of endocrine mechanisms. These include increase in progesterone, human placental lactogen (hPL) and prolactin (PRL) serum levels. In contrast, levels of pituitary hormones such as follicle stimulating hormone (FSH), luteinizing hormone (LH) and human chorionic gonadotropin (hCG) produced by the placenta are decreasing in the mother prior to childbirth. Besides, vascular factors also play a crucial role. Peritumoral brain edema (PTBE), with well-known causative association with vascular endothelial growth factor (VEGF), can often be seen both with imaging and in the surgical specimens. Our aim is to assess published research on this topic including diagnostic and therapeutic guidelines, and to provide a clinically useful overview on the pathophysiology and biological behaviour of this rare complication of pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.