Evidence map›Paper›PMID 28744361›Full record

ArticleMedical gas research

Argon attenuates the emergence of secondary injury after traumatic brain injury within a 2-hour incubation period compared to desflurane: an

Linda Grüßer, Rosmarie Blaumeiser-Debarry, Matthias Krings, Benedikt Kremer, Anke Höllig, Rolf Rossaint, Mark Coburn

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Medical gas research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Positive Effects of Argon Inhalation After Traumatic Brain Injury in Rats.International journal of molecular sciences · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Linda GrüßerDepartment of Anesthesiology, RWTH Aachen University Hospital, Aachen, Germany.ORCID 0000-0002-1274-5611
Rosmarie Blaumeiser-DebarryDepartment of Anesthesiology, RWTH Aachen University Hospital, Aachen, Germany.
Matthias KringsDepartment of Anesthesiology and Intensive Care, Medizinisches Zentrum StaedteRegion Aachen, Wuerselen, Germany.
Benedikt KremerDepartment of Neurosurgery, RWTH Aachen University Hospital, Aachen, Germany.
Anke HölligDepartment of Neurosurgery, RWTH Aachen University Hospital, Aachen, Germany.
Rolf RossaintDepartment of Anesthesiology, RWTH Aachen University Hospital, Aachen, Germany.
Mark CoburnDepartment of Anesthesiology, RWTH Aachen University Hospital, Aachen, Germany.
RWTH Aachen University · DEUniversitätsklinikum Aachen · DELuisenhospital Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite years of research, treatment of traumatic brain injury (TBI) remains challenging. Considerable data exists that some volatile anesthetics might be neuroprotective. However, several studies have also revealed a rather neurotoxic profile of anesthetics. In this study, we investigated the effects of argon 50%, desflurane 6% and their combination in an

Indexed as

argondesfluranein vitro modelneuroprotectionorganotypic hippocampal brain slicespropidium iodidesecondary injurytraumatic brain injury

Identifiers

PMID28744361
PMCPMC5510299
OpenAlexW2716295354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.