Evidence map›Paper›PMID 28744344›Full record

ArticleWorld journal of gastrointestinal endoscopy2017

Use of volumetric laser endomicroscopy for dysplasia detection at the gastroesophageal junction and gastric cardia.

Nina Gupta, Uzma Siddiqui, Irving Waxman, Christopher Chapman, Ann Koons, Vesta Valuckaite, Shu-Yuan Xiao, Namrata Setia, John Hart, Vani Konda

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nina GuptaNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Uzma SiddiquiNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Irving WaxmanNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Christopher ChapmanNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Ann KoonsNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Vesta ValuckaiteNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Shu-Yuan XiaoNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Namrata SetiaNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
John HartNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
Vani KondaNina Gupta, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60616, United States.
University of Chicago Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine specific volumetric laser endomicroscopy (VLE) imaging features associated with neoplasia at the gastroesophageal junction (GEJ) and gastric cardia.

methodsDuring esophagogastroduodenoscopy for patients with known or suspected Barrett's esophagus, VLE was performed before biopsies were taken at endoscopists' discretion. The gastric cardia was examined on VLE scan from the GEJ (marked by top of gastric folds) to 1 cm distal from the GEJ. The NinePoints VLE console was used to analyze scan segments for characteristics previously found to correlate with normal or abnormal mucosa. Glands were counted individually. Imaging features identified on VLE scan were correlated with biopsy results from the GEJ and cardia region.

resultsThis study included 34 cases. Features characteristic of the gastric cardia (gastric rugae, gastric pit architecture, poor penetration) were observed in all (100%) scans. Loss of classic gastric pit architecture was common and there was no difference between those with neoplasia and without (100%

conclusionThe transition from esophagus to gastric cardia is reliably identified on VLE. Histologically abnormal cardia mucosa produces abnormal VLE features. Optical coherence tomography algorithms can be expanded for use at the GEJ/cardia.

Indexed as

Barrett’sCardiaGastroesophageal junctionNeoplasiaOptical coherence tomographyVolumetric laser endomicroscopy

Identifiers

PMID28744344
PMCPMC5507823
OpenAlexW2737160894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.