Evidence map›Paper›PMID 28744338›Full record

ReviewOxidative medicine and cellular longevity2017

Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression.

Julie Chao, Youming Guo, Pengfei Li, Lee Chao

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Clinical Significance of Serum Kallistatin and ENOX1 Levels in Patients with Coronary Heart Disease.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021
    Article
  11. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside modulated human umbilical vein endothelial cells injury under oxidative stress.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2020
    Article
  12. Review
  13. MicroRNA Networks Modulate Oxidative Stress in Cancer.International journal of molecular sciences · 2019
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julie ChaoDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0001-7294-2636
Youming GuoDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA.
Pengfei LiDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA.
Lee ChaoDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA.
Medical University of South Carolina · US

Funding

Kallistatin in Vascular InjuryR01HL118516 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CHAO, JULIE · 2014 to 2017
$1.5M
NHLBI NIH HHS R01 HL118516
6 · The paper itself

Abstract

Kallistatin is an endogenous protein that regulates differential signaling pathways and a wide spectrum of biological activities via its two structural elements: an active site and a heparin-binding domain. Kallistatin via its heparin-binding site inhibits vascular inflammation and oxidative stress by antagonizing TNF-

Indexed as

AgingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsHumansMiceMicroRNAsNeoplasmsOxidative StressRNA, HelminthRNA, NeoplasmSerpinsCaenorhabditis elegans ProteinskallistatinMicroRNAsMIRN21 microRNA, humanMIRN34 microRNA, humanRNA, HelminthRNA, NeoplasmSerpins

Identifiers

PMID28744338
PMCPMC5506461
OpenAlexW2734000757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.