Evidence map›Paper›PMID 28744286›Full record

ReviewFrontiers in immunology2017

A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model.

Bert A 't Hart, Jordon Dunham, Bart W Faber, Jon D Laman, Jack van Horssen, Jan Bauer, Yolanda S Kap

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Bert A 't HartDepartment of Immunobiology, Biomedical Primate Research Center, Rijswijk, Netherlands.
Jordon DunhamDepartment of Immunobiology, Biomedical Primate Research Center, Rijswijk, Netherlands.
Bart W FaberDepartment of Parasitology, Biomedical Primate Research Center, Rijswijk, Netherlands.
Jon D LamanDepartment of Neuroscience, University of Groningen, University Medical Center, Groningen, Netherlands.
Jack van HorssenDepartment of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, Netherlands.
Jan BauerDepartment of Neuroimmunology, Brain Research Institute, Medical University Vienna, Vienna, Austria.
Yolanda S KapDepartment of Immunobiology, Biomedical Primate Research Center, Rijswijk, Netherlands.
Biomedical Primate Research Centre · NLUniversity of Groningen · NLAmsterdam UMC Location VUmc · NLMedical University of Vienna · ATUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The absence of pathological hallmarks of progressive multiple sclerosis (MS) in commonly used rodent models of experimental autoimmune encephalomyelitis (EAE) hinders the development of adequate treatments for progressive disease. Work reviewed here shows that such hallmarks are present in the EAE model in marmoset monkeys (

Indexed as

animal modelB celldemyelinationEpstein–Barr virusexperimental autoimmune encephalomyelitismultiple sclerosis

Identifiers

PMID28744286
PMCPMC5504154
OpenAlexW2735779622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.