ArticleFrontiers in microbiology2017
Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation.
Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
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Who cites it
87 citing papers in PubMed.
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- Spatial metabolomics reveals the role of penicillic acid in cheese-rind microbiome disruption by a spoilage fungus.mSystems · 2026Article
- Green Synthesis and Bioactivity Evaluation of Silver Nanoparticles from Stevia rebaudiana and the Endophyte Aspergillus versicolor.Current microbiology · 2026Article
- Biodiversity and Biological Interactions of Actinobacteria Associated with Deep Sea and Intertidal Marine Invertebrates.Marine drugs · 2025Article
- Microbial consortium involving Pseudomonas and Bacillus: strain selection and the effect of co-cultivation on biocontrol activity against phytopathogens and the composition of metabolic extracts.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- High-throughput profiling of fungal diversity and physicochemical dynamics in strong-aroma Daqu.AMB Express · 2025Article
- Spatial Metabolomics Reveals the Role of Penicillic Acid in Cheese Rind Microbiome Disruption by a Spoilage Fungus.bioRxiv : the preprint server for biology · 2025Article
- Metabolomic profiling and antimicrobial investigation ofNarra J · 2025Article
- Global survey of secondary metabolism inPNAS nexus · 2025Article
- Regulation and induction of fungal secondary metabolites: a comprehensive review.Archives of microbiology · 2025Review
- Current Approaches and Implications in Discovery of Novel Bioactive Products from Microbial Sources.Current microbiology · 2025Review
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- The Mutually Inspiring Biological and Chemical Synthesis of Fungal Bicyclo[2.2.2]diazaoctane Indole Alkaloids.Chemical reviews · 2025Review
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- Advanced Technologies for Large Scale Supply of Marine Drugs.Marine drugs · 2025Review
- Integrative multi-omics analysis of the microbiome and metabolome in bronchoalveolar lavage fluid from patients with early-stage lung cancer.Frontiers in cellular and infection microbiology · 2025Article
- Volatile Organic Compounds Produced by Co-Culture ofInternational journal of molecular sciences · 2024Article
- Inhibitory activity of bacterial lipopeptides against Fusarium oxysporum f.sp. Strigae.BMC microbiology · 2024Article
- Article
- Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine CyanobacteriumACS chemical biology · 2024Article
27 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The frequent re-isolation of known compounds is one of the major challenges in drug discovery. Many biosynthetic genes are not expressed under standard culture conditions, thus limiting the chemical diversity of microbial compounds that can be obtained through fermentation. On the other hand, the competition during co-cultivation of two or more different microorganisms in most cases leads to an enhanced production of constitutively present compounds or an accumulation of cryptic compounds that are not detected in axenic cultures of the producing strain under different fermentation conditions. Herein, we report the dual induction of newly detected bacterial and fungal metabolites by the co-cultivation of the marine-derived fungal isolate
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