ReviewFrontiers in physiology2017
Is It Time to Begin a Public Campaign Concerning Frailty and Pre-frailty? A Review Article.
Review in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Evidence on non-pharmacological interventions for preventing or reversing physical frailty in community-dwelling older adults aged over 50 years: overview of systematic reviews.BMC geriatrics · 2025Pooled it
- Systematic review and meta-analysis on the prevalence and risk factors of oral frailty among older adults.Frontiers in medicine · 2025Pooled it
- Community-based exercises improve health status in pre-frail older adults: A systematic review with meta-analysis.BMC geriatrics · 2024Pooled it
- The prevalence and influencing factors of frailty in patients with chronic kidney disease: a systematic review and meta-analysis.International urology and nephrology · 2024Pooled it
- The prevalence of frailty in patients on hemodialysis: a systematic review and meta-analysis.International urology and nephrology · 2020Pooled it
- Low 25-hydroxyvitamin D levels and the risk of frailty syndrome: a systematic review and dose-response meta-analysis.BMC geriatrics · 2018Pooled it
- Frailty as a mortality predictor in older adults with COVID-19: A systematic review and meta-analysis of cohort studies.Geriatric nursing (New York, N.Y.)Pooled it
- Comprehensive geriatric assessment for people living with HIV and frailty: A mixed-methods feasibility randomized controlled trial.HIV medicine · 2026Trial
- Effects of a multicomponent training and detraining on frailty status, physical activity level, sedentary behavior patterns and physical performance of pre-frail older adults: a randomized controlled trial.European geriatric medicine · 2024Trial
- Effects of a physical activity programme to prevent physical performance decline in onco-geriatric patients: a randomized multicentre trial.Journal of cachexia, sarcopenia and muscle · 2019Trial
- Intensity-Dependent Effects of a Six-Week Balance Exercise Program in Elderly Women.International journal of environmental research and public health · 2018Trial
- Influencing factors of oral frailty in Chinese maintenance hemodialysis patients: a Bayesian network analysis.Renal failure · 2026Article
- Patient selection for complex, high-risk indicated percutaneous coronary intervention procedures: an overview.European heart journal supplements : journal of the European Society of Cardiology · 2026Article
- Metabolic syndrome duration and risk of frailty among midlife women: the Study of Women's Health Across the Nation.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Impact of social isolation on older outpatients during the COVID-19 pandemic.Einstein (Sao Paulo, Brazil) · 2026Article
- Association of health promotion behaviors with frailty in Chinese middle-aged and older adults: a cross-sectional study.BMC geriatrics · 2025Article
- Influence of different anesthetic depth on postoperative delirium in elderly pre-frail patients undergoing abdominal surgery.Perioperative medicine (London, England) · 2025Article
- Frailty identification using a sensor-based upper-extremity function test: a deep learning approach.Scientific reports · 2025Article
- Synergistic Effects of Omega-3 Fatty Acids and Physical Activity on Oxidative Stress Markers and Antioxidant Mechanisms in Aged Rats.Nutrients · 2024Article
- Older people's perspectives on frailty screening in primary care settings - a citizens' jury study.BMC primary care · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is a state that encompasses losses in physical, psychological or social domains. Therefore, frail people demonstrate a reduced potential to manage external stressors and to respond to life incidents. Consequently, such persons are prone to various adverse consequences such as falls, cognitive decline, infections, hospitalization, disability, institutionalization, and death. Pre-frailty is a condition predisposing and usually preceding the frailty state. Early detection of frailty (i.e., pre-frailty) may present an opportunity to introduce effective management to improve outcomes. Exercise training appears to be the basis of such management in addition to periodic monitoring of food intake and body weight. However, various nutritional supplements and other probable interventions, such as treatment with vitamin D or androgen, require further investigation. Notably, many societies are not conscious of frailty as a health problem. In fact, people generally do not realize that they can change this unfavorable trajectory to senility. As populations age, it is reasonable to begin treating frailty similarly to other population-affecting disorders (e.g., obesity, diabetes or cardiovascular diseases) and implement appropriate preventative measures. Social campaigns should inform societies about age-related frailty and pre-frailty and suggest appropriate lifestyles to avoid or delay these conditions. In this article, we review current information concerning therapeutic interventions in frailty and pre-frailty and discuss whether a greater public awareness of such conditions and some preventative and therapeutic measures may decrease their prevalence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.