ArticlePatient preference and adherence2017
Pattern of statin use changes following media coverage of its side effects.
Article in Patient preference and adherence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Changes in LDL-C levels among primary health care patients with hypertension, coronary artery disease, and diabetes during a 36-month follow-up.Scandinavian journal of primary health care · 2026Article
- Article
- Measuring patient adherence in secondary prevention of atherosclerotic cardiovascular disease: a scoping review.BMJ open · 2026Article
- Short- and Long-Term Statin Persistence and Determinants in Patients Initiating Statin Therapy.Medeniyet medical journal · 2025Article
- Lipid Lowering Therapy Utilization and Lipid Goal Attainment in Women.Current atherosclerosis reports · 2025Review
- Changes in doxylamine-pyridoxine dispensation in Ontario following media attention: Time-series analysis.Canadian family physician Medecin de famille canadien · 2025Article
- Artificial Intelligence-Enabled Analysis of Statin-Related Topics and Sentiments on Social Media.JAMA network open · 2023Article
- Statin-related Muscle Toxicity: An Evidence-based Review.TouchREVIEWS in endocrinology · 2022Review
- Older people's attitudes towards deprescribing cardiometabolic medication.BMC geriatrics · 2021Article
- Statins in a Distorted Mirror of Media.Current atherosclerosis reports · 2020Review
- Is polypharmacy an increasing burden in chronic kidney disease? The German experience.Clinical kidney journal · 2019Article
- Recent Approaches to Improve Medication Adherence in Patients with Coronary Heart Disease: Progress Towards a Learning Healthcare System.Current atherosclerosis reports · 2018Review
- Nonadherence in the Learning Healthcare System: Avoiding a Mountain by Seeing the Bumps.Circulation. Cardiovascular quality and outcomes · 2017Article
- Older Adult Attitudes toward Deprescribing Statins in Primary Cardiovascular Prevention Versus General Medications.Gerontology & geriatric medicineArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe media plays a role in shaping opinions about medical decisions, for example, whether to initiate or stop treatment. An association between negative media attention and statin discontinuation has been demonstrated, but it may differ depending on the reason for prescription and whether the user is new (incident) or long term (prevalent).
aimThe aim of this study is to explore whether a Danish newspaper article featuring the side effects of statins affects statin discontinuation in incident versus prevalent users, with the reason for prescription also taken into account.
methodsThe study relies on a quasi-experimental design and uses registry data on statin purchases to explore discontinuation and treatment duration. As a proxy for reason for prescription, data on filled prescriptions and hospital diagnoses from a Danish registry were used. We compared statin discontinuation in all statin users in Denmark in 2007 before the media event (n=343,438) and after it in 2008 (n=404,052).
resultsCompared to 2007, statin discontinuation among prevalent users in 2008 increased by 2.97 percentage points (pp). The change in discontinuation varied with the indication for statin use. Those with myocardial infarction had the smallest increase (1.98 pp) and those with hypercholesterolemia or primary hypertension had the largest increase (3.54 pp). Incident statin users had a higher level of discontinuation and a larger difference in discontinuation between 2007 and 2008. Compared to 2007, more people (5.52 pp) discontinued statin treatment in 2008. Again, those with myocardial infarction had the smallest decrease in statin discontinuation (1.49 pp), while those with a potential atherosclerotic condition (7.05 pp) and hypercholesterolemia or primary hypertension (6.10 pp) had the largest increase.
conclusionStatin discontinuation increased in 2008 following a media event, but especially among individuals prescribed statins for primary prevention and among new statin users.
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