Evidence map›Paper›PMID 28743945›Full record

ArticleScientific reports2017

Lithium Sensitive ORAI1 Expression, Store Operated Ca

Lisann Pelzl, Stefan Hauser, Bhaeldin Elsir, Basma Sukkar, Itishri Sahu, Yogesh Singh, Philip Höflinger, Rosi Bissinger, Mohamed Jemaà, Christos Stournaras and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Chorein Regulates Key Osteoblast Genes in UMR-106 Cells.Cell biochemistry and biophysics · 2026
    Article
  3. CaBiomedicines · 2025
    Review
  4. Review
  5. Review
  6. Neuronal Store-Operated Calcium Channels.Molecular neurobiology · 2023
    Review
  7. Article
  8. Yeast as a Model to Find New Drugs and Drug Targets forInternational journal of molecular sciences · 2022
    Review
  9. Article
  10. Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain.International journal of molecular sciences · 2021
    Article
  11. Article
  12. Effect of MgClInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Article
  15. Decreased NaScientific reports · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Lisann PelzlDepartment of Physiology I, University of Tübingen, Tübingen, Germany.
Stefan HauserGerman Center for Neurodegenerative Diseases, Tübingen, Germany.ORCID 0000-0002-1022-7482
Bhaeldin ElsirDepartment of Physiology I, University of Tübingen, Tübingen, Germany.
Basma SukkarDepartment of Physiology I, University of Tübingen, Tübingen, Germany.ORCID 0000-0003-4945-9333
Itishri SahuDepartment of Physiology I, University of Tübingen, Tübingen, Germany.
Yogesh SinghDepartment of Physiology I, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-6919-6273
Philip HöflingerDepartment of Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Rosi BissingerDepartment of Physiology I, University of Tübingen, Tübingen, Germany.
Mohamed JemaàDepartment of Physiology I, University of Tübingen, Tübingen, Germany.
Christos StournarasDepartment of Physiology I, University of Tübingen, Tübingen, Germany.
Ludger SchölsGerman Center for Neurodegenerative Diseases, Tübingen, Germany.
Florian LangDepartment of Physiology I, University of Tübingen, Tübingen, Germany. florian.lang@uni-tuebingen.de.ORCID 0000-0003-2962-1540
University of Tübingen · DEGerman Center for Neurodegenerative Diseases · DEHertie Institute for Clinical Brain Research · DEUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chorea-Acanthocytosis (ChAc), a neurodegenerative disorder, results from loss-of-function-mutations of chorein-encoding gene VPS13A. In tumour cells chorein up-regulates ORAI1, a Ca

Indexed as

ApoptosisBenzoatesBridged Bicyclo Compounds, HeterocyclicCalciumCell DeathCell DifferentiationFibroblastsHealthy VolunteersHumansLithiumNeoplasm ProteinsNeuroacanthocytosisNeuronsORAI1 ProteinStromal Interaction Molecule 12-cyclopentyl-4-(5-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl)-benzoic acidBenzoatesBridged Bicyclo Compounds, HeterocyclicCalciumLithiumNeoplasm ProteinsORAI1 ProteinORAI1 protein, humanSTIM1 protein, humanStromal Interaction Molecule 1

Identifiers

PMID28743945
PMCPMC5526875
OpenAlexW2738784940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.