Evidence map›Paper›PMID 28743937›Full record

ArticleScientific reports2017

Photo-irradiated caffeic acid exhibits antimicrobial activity against Streptococcus mutans biofilms via hydroxyl radical formation.

Keisuke Nakamura, Midori Shirato, Taro Kanno, Peter Lingström, Ulf Örtengren, Yoshimi Niwano

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  4. Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Keisuke NakamuraLaboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, 4-1 Seiryo, Aoba-ku, Sendai, 980-8575, Japan. keisuke@m.tohoku.ac.jp.
Midori ShiratoLaboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, 4-1 Seiryo, Aoba-ku, Sendai, 980-8575, Japan.
Taro KannoDivision of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry, 4-1 Seiryo, Aoba-ku, Sendai, 980-8575, Japan.
Peter LingströmDepartment of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Gothenburg, Sweden.
Ulf ÖrtengrenDepartment of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Gothenburg, Sweden.
Yoshimi NiwanoLaboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, 4-1 Seiryo, Aoba-ku, Sendai, 980-8575, Japan.
Tohoku University · JPUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An antimicrobial technique based on photo-oxidation of caffeic acid (CA) has recently been developed, but its effect on biofilm-forming bacteria is unknown. The present study aimed to evaluate the effect of photo-irradiated CA against Streptococcus mutans (cariogenic bacteria) biofilm as it relates to hydroxyl radical formation. S. mutans biofilms grown on hydroxyapatite disks were immersed in CA solution (0-2 mg/mL) and irradiated with LED light at wavelengths of 365, 385, and 400 nm and at irradiances of 500, 1000, and 2000 mW/cm

Indexed as

Anti-Bacterial AgentsBiofilmsCaffeic AcidsDurapatiteHydroxyl RadicalLightMicrobial ViabilityStreptococcus mutansAnti-Bacterial Agentscaffeic acidCaffeic AcidsDurapatiteHydroxyl Radical

Identifiers

PMID28743937
PMCPMC5527086
OpenAlexW2739477666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.