Evidence map›Paper›PMID 28743795›Full record

ArticleMolecular systems biology2017

Capturing protein communities by structural proteomics in a thermophilic eukaryote.

Panagiotis L Kastritis, Francis J O'Reilly, Thomas Bock, Yuanyue Li, Matt Z Rogon, Katarzyna Buczak, Natalie Romanov, Matthew J Betts, Khanh Huy Bui, Wim J Hagen and 7 more

Abstract read
In one paragraph

Article in Molecular systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Mapping the architecture of protein complexes inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Visual exoproteomics ofbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Review
  8. Identification and Regulation of a Hepatic Lipogenic Metabolon.bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. A Photo-Caged Cross-Linker for Identifying Protein-Protein Interactions.Chembiochem : a European journal of chemical biology · 2024
    Article
  15. Disorder-to-order active site capping regulates the rate-limiting step of the inositol pathway.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Panagiotis L KastritisEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0002-1463-8422
Francis J O'ReillyEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
Thomas BockEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0002-9314-5318
Yuanyue LiEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0001-5971-0355
Matt Z RogonEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
Katarzyna BuczakEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
Natalie RomanovEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0003-3749-2654
Matthew J BettsCell Networks, Bioquant & Biochemie Zentrum Heidelberg, Heidelberg University, Heidelberg, Germany.
Khanh Huy BuiEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0001-8231-3016
Wim J HagenEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
Marco L HennrichEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0003-2853-9748
Marie-Therese MackmullEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.ORCID 0000-0003-2928-1144
Juri RappsilberChair of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.ORCID 0000-0001-5999-1310
Robert B RussellCell Networks, Bioquant & Biochemie Zentrum Heidelberg, Heidelberg University, Heidelberg, Germany.
Peer BorkEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
Martin BeckEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany martin.beck@embl.de gavin@embl.de.ORCID 0000-0002-7397-1321
Anne-Claude GavinEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany martin.beck@embl.de gavin@embl.de.ORCID 0000-0003-4917-2340

Funding

Wellcome Trust 103139Wellcome Trust 103139/Z/13/ZWellcome Trust 203149
6 · The paper itself

Abstract

The arrangement of proteins into complexes is a key organizational principle for many cellular functions. Although the topology of many complexes has been systematically analyzed in isolation, their molecular sociology

Indexed as

Cellular MicroenvironmentChaetomiumCross-Linking ReagentsCryoelectron MicroscopyFatty Acid Synthase, Type IIFungal ProteinsMass SpectrometryModels, MolecularMultiprotein ComplexesProtein Interaction MappingProtein Interaction MapsProteomicsSubcellular FractionsSystems BiologyCross-Linking ReagentsFatty Acid Synthase, Type IIFungal ProteinsMultiprotein Complexescomputational modelingcryo‐electron microscopyfatty acid synthaseinteraction proteomicsmetabolon

Identifiers

PMID28743795
PMCPMC5527848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.