Evidence map›Paper›PMID 28743763›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K

Moza M Al-Owais, Nishani T Hettiarachchi, Hannah M Kirton, Matthew E Hardy, John P Boyle, Jason L Scragg, Derek S Steele, Chris Peers

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Frontiers in physiology · 2022
    Article
  3. Article
  4. Review
  5. Article
  6. Air Pollution and Cardiac Diseases: A Review of Experimental Studies.Dose-response : a publication of International Hormesis Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Moza M Al-OwaisDivision of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
Nishani T HettiarachchiDivision of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
Hannah M KirtonFaculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Matthew E HardyFaculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
John P BoyleDivision of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
Jason L ScraggDivision of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and.
Derek S SteeleFaculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Chris PeersDivision of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom; and c.s.peers@leeds.ac.uk.
University of Leeds · GB

Funding

British Heart Foundation PG/13/61/30410
6 · The paper itself

Abstract

Exposure to CO causes early afterdepolarization arrhythmias. Previous studies in rats have indicated that arrhythmias arose as a result of augmentation of the late Na

Indexed as

AnimalsArrhythmias, CardiacCarbon MonoxideERG1 Potassium ChannelGuinea PigsHEK293 CellsHumansMembrane PotentialsMetalloporphyrinsMyocytes, CardiacNitric OxideOrganometallic CompoundsPeroxynitrous Acid5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chlorideCarbon MonoxideERG1 Potassium ChannelKCNH2 protein, humanMetalloporphyrinsNitric OxideOrganometallic CompoundsPeroxynitrous Acidtricarbonyldichlororuthenium (II) dimerarrhythmianitric oxidepotassium channel

Identifiers

PMID28743763
PMCPMC5636698
OpenAlexW2735908423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.