Evidence map›Paper›PMID 28743761›Full record

ArticleGenetics2017

Naturally Segregating Variation at

Chad A Highfill, Jonathan H Tran, Samantha K T Nguyen, Taylor R Moldenhauer, Xiaofei Wang, Stuart J Macdonald

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Dynamic Changes in Gene Expression Through Aging inbioRxiv : the preprint server for biology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The UDP-Glycosyltransferase Family inFrontiers in physiology · 2021
    Article
  10. Article
  11. Article
  12. A Fly's Eye View of Natural and Drug Reward.Frontiers in physiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chad A HighfillDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66047.
Jonathan H TranDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66047.
Samantha K T NguyenDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66047.
Taylor R MoldenhauerDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66047.
Xiaofei WangDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66047.
Stuart J MacdonaldDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66047 sjmac@ku.edu.ORCID 0000-0002-9421-002X
University of Kansas · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUSAN J. BROWN · 2012 to 2026
$63.0M
Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HOLMSTROM, ERIK D · 2012 to 2021
$22.1M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
A resource for the genetic analysis of complex traitsR01OD010974 · OD · UNIVERSITY OF KANSAS LAWRENCE · PI LONG, ANTHONY DOUGLAS, MACDONALD, STUART JOHN · 2012 to 2019
$3.1M
NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM103638NIGMS NIH HHS R01 GM084947NIH HHS P40 OD018537NIH HHS R01 OD010974
6 · The paper itself

Abstract

Identifying the sequence polymorphisms underlying complex trait variation is a key goal of genetics research, since knowing the precise causative molecular events allows insight into the pathways governing trait variation. Genetic analysis of complex traits in model systems regularly starts by constructing QTL maps, but generally fails to identify causative sequence polymorphisms. Previously we mapped a series of QTL contributing to resistance to nicotine in a

Indexed as

Polymorphism, GeneticQuantitative Trait LociAnimalsDrosophila melanogasterDrosophila ProteinsDrug ResistanceFrameshift MutationINDEL MutationIntestinal MucosaLoss of Function MutationNicotineDrosophila ProteinsNicotineCRISPRfunctional validationQTL mappingRNAixenobiotics

Identifiers

PMID28743761
PMCPMC5586381
OpenAlexW2953101525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.