Evidence map›Paper›PMID 28743659›Full record

Trial reportJournal of pain and symptom management2017

A Randomized Clinical Trial of Caregiver-Delivered Reflexology for Symptom Management During Breast Cancer Treatment.

Gwen Wyatt, Alla Sikorskii, Irena Tesnjak, Dawn Frambes, Amanda Holmstrom, Zhehui Luo, David Victorson, Deimante Tamkus

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of pain and symptom management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 9 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 9 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Reflexology in oncological treatment - a systematic review.BMC complementary medicine and therapies · 2024
    Pooled it
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  3. Utility of the Patient-Reported Outcomes Measurement Information System (PROMIS) to measure primary health outcomes in cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
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  9. Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement of the SIO Clinical Practice Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Guideline
  10. Trial
  11. Family caregivers of those with cancer: quality of life outcomes from a sequential multiple assignment randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
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  14. Symptom response analysis of a randomized controlled trial of reflexology for symptom management among women with advanced breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Trial
  15. Healthcare service utilization and work-related productivity in reflexology intervention for advanced breast cancer women.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gwen WyattCollege of Nursing, Michigan State University, East Lansing, Michigan, USA. Electronic address: Gwyatt@msu.edu.
Alla SikorskiiCollege of Nursing, University of Arizona, Tucson, Arizona, USA.
Irena TesnjakDepartment of Statistics and Probability, Michigan State University, East Lansing, Michigan, USA.
Dawn FrambesCollege of Nursing, Michigan State University, East Lansing, Michigan, USA.
Amanda HolmstromDepartment of Communication, Michigan State University, East Lansing, Michigan, USA.
Zhehui LuoDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA.
David VictorsonFeinberg School of Medicine, Northwestern University, Evanston, Illinois, USA.
Deimante TamkusCollege of Human Medicine, Michigan State University, East Lansing, Michigan, USA.
Michigan State University · USNorthwestern University · USUniversity of Arizona · US

Funding

Home-Based Symptom Management via Reflexology for Advanced Breast Cancer PatientsR01CA157459 · NCI · MICHIGAN STATE UNIVERSITY · PI WYATT, GWEN KARILYN · 2011 to 2015
$2.5M
NCI NIH HHS R01 CA157459
6 · The paper itself

Abstract

purposeThe objective of this study was to determine the effects of a home-based reflexology intervention delivered by a friend/family caregiver compared with attention control on health-related quality of life of women with advanced breast cancer undergoing chemotherapy, targeted and/or hormonal therapy.

methodsPatient-caregiver dyads (N = 256) were randomized to four weekly reflexology sessions or attention control. Caregivers in the intervention group were trained in a 30-minute protocol. During the four weeks, both groups had telephone symptom assessments, and intervention group had fidelity assessments. The intervention effects were assessed using linear mixed-effects models at weeks 5 and 11 for symptom severity and interference with daily activities, functioning, social support, quality of patient-caregiver relationship, and satisfaction with life.

resultsSignificant reductions in average symptom severity (P = 0.02) and interference (P < 0.01) over 11 weeks were found in the reflexology group compared with control, with no group differences in functioning, social support, quality of relationship, or satisfaction with life at weeks 5 and 11. Stronger quality of relationship was associated with lower symptom interference in the entire sample (P = 0.02), but controlling for it did not diminish the effect of intervention on symptoms. Significant reductions in symptom severity in the reflexology group compared with attention control were seen during weeks 2-5 but were reduced at Week 11. DISCUSSION: Efficacy findings of caregiver-delivered reflexology with respect to symptom reduction open a new evidence-based avenue for home-based symptom management.

Indexed as

CaregiversMassageSelf CareActivities of Daily LivingBreast NeoplasmsFemaleHumansInterpersonal RelationsLinear ModelsMaleMiddle AgedPersonal SatisfactionSeverity of Illness IndexSocial SupportTreatment Outcomebreast cancerhome-basedinterventionlay caregiversreflexologySymptom management

Identifiers

PMID28743659
PMCPMC5650941
OpenAlexW2738293023

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.