ArticleBMC women's health2017
Risk factors and a prediction model for lower limb lymphedema following lymphadenectomy in gynecologic cancer: a hospital-based retrospective cohort study.
Article in BMC women's health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Effectiveness of physical therapy for lower limb lymphedema in gynecological cancer survivors: a systematic review of randomized controlled trials.Frontiers in oncology · 2026Pooled it
- Risk factors for lower limb lymphedema after gynecological cancer treatment: a systematic review.Frontiers in oncology · 2025Pooled it
- Trial
- Feasibility of a Pilot Randomized Controlled Trial Examining a Multidimensional Intervention in Women with Gynecological Cancer at Risk of Lymphedema.Current oncology (Toronto, Ont.) · 2021Trial
- Lymphatic disruption drives lung transplant fibrosis through interleukin-1-mediated hyaluronan accumulation.Science translational medicine · 2026Article
- Lymphatic Mapping and Preservation: Strategies to Reduce Lymphatic Damage and Its Consequences in Lower Limb Surgery.Plastic and reconstructive surgery. Global open · 2025Article
- Exercise interventions for the treatment of lower limb lymphoedema after treatment for gynaecological cancers.The Cochrane database of systematic reviews · 2025Article
- Clinical Relevance of Animal Models of Lymphatic Dysfunction and Lymphedema.Microcirculation (New York, N.Y. : 1994) · 2025Review
- A gene-based predictive model for lymph node metastasis in cervical cancer: superior performance over imaging techniques.Journal of translational medicine · 2025Article
- Incidence and predictors of lower extremity lymphedema after postoperative radiotherapy for prostate cancer.Radiation oncology (London, England) · 2025Article
- Treatment outcomes in lower limb lymphedema misdiagnosed as iliac vein compression syndrome: A retrospective analysis.PloS one · 2025Article
- Self-management of lower limb lymphedema at home following gynecologic cancer surgery: a qualitative study of women's experiences and challenges.Frontiers in psychology · 2025Article
- A Nomogram Based on Fibrinogen-to-Neutrophil Ratio as a Novel Predictor of Lymph Node Metastasis in Patients with Cervical Cancer and Type 2 Diabetes Mellitus.Cancer management and research · 2025Article
- Analysis of Risk Factors of Lymphedema After Surgical Treatment in Cervical Cancer: A Case-Control Retrospective Study.International journal of general medicine · 2025Article
- Post treatment lower limb lymphedema in carcinoma cervix.Ecancermedicalscience · 2025Article
- Etiology and treatment of cancer-related secondary lymphedema.Clinical & experimental metastasis · 2024Review
- A Retrospective Study of Complications Following Pelvic and Para-Aortic Lymphadenectomy in Gynecologic Oncology.World journal of oncology · 2024Article
- Article
- A preoperative nomogram predicting risk of lymph node metastasis for early-stage cervical cancer.BMC women's health · 2023Article
- Evaluation of incontinence and lymphedema in gynecological cancer patients along with their impact on the quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLower limb lymphedema (LLL) is a chronic and incapacitating condition afflicting patients who undergo lymphadenectomy for gynecologic cancer. This study aimed to identify risk factors for LLL and to develop a prediction model for its occurrence.
methodsPelvic lymphadenectomy (PLA) with or without para-aortic lymphadenectomy (PALA) was performed on 366 patients with gynecologic malignancies at Yaizu City Hospital between April 2002 and July 2014; we retrospectively analyzed 264 eligible patients. The intervals between surgery and diagnosis of LLL were calculated; the prevalence and risk factors were evaluated using the Kaplan-Meier and Cox proportional hazards methods. We developed a prediction model with which patients were scored and classified as low-risk or high-risk.
resultsThe cumulative incidence of LLL was 23.1% at 1 year, 32.8% at 3 years, and 47.7% at 10 years post-surgery. LLL developed after a median 13.5 months. Using regression analysis, body mass index (BMI) ≥25 kg/m
conclusionBMI ≥25 kg/m
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