ArticlePloS one2017
Taste preference changes throughout different life stages in male rats.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Aging effects on emotionality, cognition and brain mononuclear cells in Sprague-Dawley rats of both sexes.npj aging · 2026Article
- Taste Propensity in Obese and Nonobese Older Adults.Aging medicine (Milton (N.S.W)) · 2025Article
- Impact of flavorants on nicotine vapor self-administration in adolescent mice: Cherry on top?The Journal of pharmacology and experimental therapeutics · 2025Article
- Contributions and future potential of animal models for geroscience research on sensory systems.GeroScience · 2025Review
- Treatment withNutrients · 2024Article
- Differences in time-intensity sensory profiles of sweet taste intensity of glucose between older and young adults.Frontiers in nutrition · 2024Article
- Two-generation exposure to a high-fat diet induces the change of salty taste preference in rats.Scientific reports · 2023Article
- Experience-dependent plasticity of gustatory insular cortex circuits and taste preferences.Science advances · 2023Article
- Spontaneous head twitches in aged rats: behavioral and molecular study.Psychopharmacology · 2022Article
- Terminal field volume of the glossopharyngeal nerve in adult rats reverts to prepruning size following microglia depletion with PLX5622.Developmental neurobiology · 2022Article
- Sucrose Preference Test as a Measure of Anhedonic Behavior in a Chronic Unpredictable Mild Stress Model of Depression: Outstanding Issues.Brain sciences · 2022Review
- Recovery of sweet taste preference in adult rats following bilateral chorda tympani nerve transection.PeerJ · 2022Article
- The umami receptor T1R1-T1R3 heterodimer is rarely formed in chickens.Scientific reports · 2021Article
- Pain influences food preference and food-related memory by activating the basolateral amygdala in rats.Experimental brain research · 2021Article
- Endogenous opioid dependence after intermittent use of glucose, sodium chloride, and monosodium glutamate solutions.Food science & nutrition · 2019Article
- Article
- The effect of enriched environment across ages: A study of anhedonia and BDNF gene induction.Genes, brain, and behavior · 2018Article
- Gustatory Dysfunction as an Early Symptom of Semantic Dementia.Dementia and geriatric cognitive disorders extraArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Taste preference, a key component of food choice, changes with aging. However, it remains unclear how this occurs. To determine differences in taste preference between rats in different life stages, we examined the consumption of taste solutions and water using a two-bottle test. Male Sprague-Dawley rats of different ages were used: juvenile (3-6 weeks), young adult (8-11 weeks), adult (17-20 weeks), middle-aged (34-37 weeks), and old-aged (69-72 weeks). The intakes of the high and low concentration solutions presented simultaneously were measured. We observed that the old-aged group had lower preference ratios for 0.3 M sucrose and 0.1 M MSG in comparison with other groups. The preference ratio for 0.03 mM QHCl was higher in the middle-aged group than in the three younger groups and higher in the old-aged group than the juvenile group. The taste preferences for HCl and NaCl did not significantly differ among the age groups. The old-aged group tended to prefer high concentrations of sucrose, QHCl, NaCl, and MSG to low concentrations, indicating age-related decline in taste sensitivity. We also aimed to investigate differences between life stages in the electrophysiological responses of the chorda tympani nerve, one of the peripheral gustatory nerves, to taste stimuli. The electrophysiological recordings showed that aging did not alter the function of the chorda tympani nerve. This study showed that aging induced alterations in taste preference. It is likely that these alterations are a result of functional changes in other peripheral taste nerves, the gastrointestinal system, or the central nervous system.
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