Evidence map›Paper›PMID 28742808›Full record

Observational studyPloS one2017

Self-help guidebook improved quality of life for patients with irritable bowel syndrome.

Antonius Schneider, Stefanie Rosenberger, Johanna Bobardt, Jessica Bungartz-Catak, Oxana Atmann, Bernhard Haller, Anne Kennedy, Paul Enck

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonius SchneiderInstitute of General Practice, University Hospital Klinikum rechts der Isar, Technische Universität München, München, Germany.ORCID http://orcid.org/0000-0002-2847-8626
Stefanie RosenbergerInstitute of General Practice, University Hospital Klinikum rechts der Isar, Technische Universität München, München, Germany.
Johanna BobardtInstitute of General Practice, University Hospital Klinikum rechts der Isar, Technische Universität München, München, Germany.
Jessica Bungartz-CatakInstitute of General Practice, University Hospital Klinikum rechts der Isar, Technische Universität München, München, Germany.
Oxana AtmannInstitute of General Practice, University Hospital Klinikum rechts der Isar, Technische Universität München, München, Germany.
Bernhard HallerInstitute for Medical Statistics and Epidemiology, University Hospital Klinikum rechts der Isar, Technische Universität München, München, Germany.
Anne KennedyNIHR Collaboration for Leadership in Applied Health Research (CLAHRC) Wessex, Faculty of Health Sciences, University of Southampton, Highfield Campus, Southampton, United Kingdom.
Paul EnckDepartment of Internal, Medicine VI: Psychosomatic Medicine and Psychotherapy, University Hospital, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary aim of our study was to evaluate the impact of a comprehensive self-help guidebook on the disease related quality of life for patients with irritable bowel syndrome (IBS). The secondary aim was to evaluate whether the guidebook is less effective in IBS patients with depression, somatization disorder or panic disorder as a psychiatric comorbidity.

methodsProspective observational study. At baseline (t1), patients filled in the ´Functional Digestive Disorders Quality of Life´ (FDDQL) questionnaire and received the IBS guidebook together with an explanation of its content and use. Depression, anxiety and somatization were evaluated with the Patient Health Questionnaire (PHQ). Three (t2) and six months (t3) later, the questionnaire was sent by mail to the patients for follow-up evaluation. Data were analyzed with repeated measures ANOVA.

results71 patients participated (74.6% female). 53 (74.6%) completed the final assessment at t3 after 6 months. The global FDDQL score increased from 49.3 (SD 12.7) at t1 to 64.3 (SD 16.0) at t3 (p < 0.001). There was a significant between-subjects effect on the global FDDQL score related to depression (p = 0.001), anxiety (p = 0.001) and somatization (p = 0.011). Thus, the quality of life of patients with psychosomatic comorbidity was lower at baseline, but showed a similar increase within the following six months.

conclusionThe self-help guidebook significantly improved measured quality of life for IBS patients. The use of screening questionnaires like PHQ might be valuable to identify patients with more complex problems. This might be helpful for them to intensify and adapt therapy. Further research has to evaluate if patients with psychological comorbidity are treated more effectively when they receive psychotherapy or specific medication in addition to the self-management guidebook.

Indexed as

Quality of LifeAdultAgedAged, 80 and overDepressionFemaleHumansIrritable Bowel SyndromeMaleMiddle AgedPanic DisorderPatient Education as TopicProspective StudiesSelf CareSomatoform DisordersSurveys and Questionnaires

Identifiers

PMID28742808
PMCPMC5526555

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.