Evidence map›Paper›PMID 28742406›Full record

Trial reportRenal failure2017

The efficacy of low-dose tadalafil in patients undergoing hemodialysis with end-stage renal disease.

Mustafa Suat Bolat, İsmail Özer, Onder Cinar, Ekrem Akdeniz, Ramazan Aşcı

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Renal failure, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mustafa Suat Bolata Department of Urology , Samsun Training and Research Hospital, Health Sciences University , Samsun , Turkey.
İsmail Özerb Department of Nephrology , Samsun Training and Research Hospital, Health Sciences University , Samsun , Turkey.
Onder Cinara Department of Urology , Samsun Training and Research Hospital, Health Sciences University , Samsun , Turkey.
Ekrem Akdeniza Department of Urology , Samsun Training and Research Hospital, Health Sciences University , Samsun , Turkey.
Ramazan Aşcıc Department of Urology , Ondokuz Mayıs University , Samsun , Turkey.
Sağlık Bilimleri Üniversitesi · TRSamsun University · TROndokuz Mayıs University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundErectile dysfunction (ED) is a disorder that is frequently observed in people with chronic kidney disease who undergo hemodialysis (HD). In the context of evidence-based medicine, we aimed to investigate the effect of low-dose tadalafil on sexual function in patients undergoing HD.

methodsThe medical records of 30 males (aged 29-65 years) with end-stage renal disease (ESRD) on a HD program, and who had received 5 mg tadalafil twice weekly, were retrospectively evaluated. Changes in erectile and ejaculatory function were evaluated using the International Erectile Function Index questionnaire, the Erection Hardness Scale (EHS), and the Male Sexual Health Questionnaire (MSHQ).

resultsThe mean age of the patients was 47.6 ± 10.1 years, their mean body mass index was 24.3 ± 4.2 kg/m

conclusionsTadalafil therapy is an effective therapeutic option in patients with ESRD who undergo HD, not only for the treatment of ED, but also for ejaculatory function, with acceptable adverse effects.

Indexed as

Renal DialysisAdultAgedEjaculationErectile DysfunctionEvidence-Based MedicineHumansKidney Failure, ChronicMaleMiddle AgedPenile ErectionRetrospective StudiesSurveys and QuestionnairesTadalafilTreatment OutcomeVasodilator AgentsTadalafilVasodilator AgentsEnd-stage renal diseasehemodialysispsychologysexual dysfunction

Identifiers

PMID28742406
PMCPMC6446171
OpenAlexW2738888580

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.