Evidence map›Paper›PMID 28742333›Full record

ArticleJournal of the American Chemical Society2017

Alkyne Hydroheteroarylation: Enantioselective Coupling of Indoles and Alkynes via Rh-Hydride Catalysis.

Faben A Cruz, Yamin Zhu, Quentin D Tercenio, Zengming Shen, Vy M Dong

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. ACS organic & inorganic Au · 2024
    Article
  4. Article
  5. Enantioselective Addition of Pyrazoles to Dienes*.Angewandte Chemie (International ed. in English) · 2021
    Article
  6. Article
  7. Enantioselective Addition of α-Nitroesters to Alkynes.Angewandte Chemie (International ed. in English) · 2021
    Article
  8. Iridium-Catalyzed Enantioselective Intermolecular Indole C2-Allylation.Angewandte Chemie (International ed. in English) · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Faben A CruzDepartment of Chemistry, University of California Irvine , Irvine, California 92697, United States.
Yamin ZhuSchool of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
Quentin D TercenioDepartment of Chemistry, University of California Irvine , Irvine, California 92697, United States.
Zengming ShenSchool of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
Vy M DongDepartment of Chemistry, University of California Irvine , Irvine, California 92697, United States.ORCID 0000-0002-8099-1048

Funding

Innovative Tools for Chemical Synthesis: Metal-Hydride Catalysis, Medicinal Motifs, and Molecular ProbesR35GM127071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vy M Dong · 2018 to 2026
$4.9M
Catalytic hydroacylation: Transforming C-H bonds into biorelevant esters and ketonesR01GM105938 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI DONG, VY M · 2013 to 2017
$1.3M
NIGMS NIH HHS R01 GM105938NIGMS NIH HHS R35 GM127071
6 · The paper itself

Abstract

We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerizes alkynes to generate a metal-allyl species that can be trapped with both aromatic and heteroaromatic nucleophiles.

Indexed as

AlkynesCatalysisHydrogenIndolesRhodiumStereoisomerismAlkynesHydrogenIndolesRhodium

Identifiers

PMID28742333
PMCPMC6824589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.