Evidence map›Paper›PMID 28741903›Full record

ArticleInfluenza and other respiratory viruses2017

The acceptability and validity of self-collected nasal swabs for detection of influenza virus infection among older adults in Thailand.

Sonal Goyal, Kriengkrai Prasert, Prabda Praphasiri, Malinee Chittaganpitch, Sunthareeya Waicharoen, Darunee Ditsungnoen, Siriluk Jaichuang, Kim A Lindblade

Open access · goldAbstract readValidation Study
In one paragraph

Article in Influenza and other respiratory viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Sonal GoyalASPPH/CDC Allan Rosenfield Global Health Fellow, Atlanta, GA, USA.
Kriengkrai PrasertNakhon Phanom Provincial Health Office, Nakhon Phanom, Thailand.
Prabda PraphasiriInfluenza Program, Thailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.
Malinee ChittaganpitchNational Institute of Health, Ministry of Public Health, Nonthaburi, Thailand.
Sunthareeya WaicharoenNational Institute of Health, Ministry of Public Health, Nonthaburi, Thailand.
Darunee DitsungnoenInfluenza Program, Thailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.
Siriluk JaichuangNakhon Phanom Provincial Health Office, Nakhon Phanom, Thailand.
Kim A LindbladeInfluenza Program, Thailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.ORCID 0000-0002-5593-0470
Ministry of Public Health · THNakhon Phanom University · THCenters for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-collection of nasal swabs could improve the timeliness of influenza virus detection in older adults.

objectivesMeasure the acceptability, adequacy, timeliness, and validity of self-collected nasal swabs among adults >65 years in Thailand.

methodsOur evaluation consisted of two parts: a one-month study among randomly selected, community-dwelling older adults to simulate community-based surveillance for acute respiratory infections (ARI); and a clinic study of older adults with ARI to evaluate the sensitivity and specificity of self-collected nasal swabs for influenza virus infection compared with healthcare worker (HCW)-collected nasal and nasopharyngeal swabs.

resultsIn the community study, 24% of participants experienced an ARI during the observation period. All (100%) participants with an ARI self-collected nasal swabs within 72 hours of symptom onset of which 92% were considered adequate samples. In the clinic study, 45% of patients with ARI presented within 72 hours of symptom onset. The sensitivity of self-collected nasal swabs for detection of influenza virus infection was 78% (95% CI 40-97) compared to nasopharyngeal and 88% (95% CI 47-100) compared to nasal swabs collected by HCWs. Specificity was 100% (95% CI 97-100) compared to both methods. Self-collection of nasal swabs was found acceptable by 99% of participants in both studies.

conclusionsSelf-collection of nasal swabs was acceptable to older adults in Thailand who were able to take adequate samples. Self-collection of nasal swabs may improve the timeliness of sample collection but lower sensitivity will need to be considered.

Indexed as

AgedAged, 80 and overFemaleHumansInfluenza A virusInfluenza, HumanMaleNasopharynxNoseRespiratory Tract InfectionsSensitivity and SpecificitySpecimen HandlingThailandelderlyinfluenzanasal swabself-collectionsensitivityThailand

Identifiers

PMID28741903
PMCPMC5596524
OpenAlexW2739028354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.