Evidence map›Paper›PMID 28741508›Full record

ArticleTrends in cancer2016

A Molecular Take on Malignant Rhabdoid Tumors.

Ming Tang, Roel G W Verhaak

Abstract readComment
In one paragraph

Article in Trends in cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ming TangDepartment of Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
Roel G W VerhaakDepartment of Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: rverhaak@mdanderson.org.

Funding

QUANTITATION OF HUMAN BRAIN TUMOR THERAPY RESPONSE BY MRP01CA085878 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHENEVERT, THOMAS L · 2001 to 2017
$31.9M
(PQ #4) Single cell barcoding for studies of study clonal evolution in glioblastomaR01CA190121 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SULMAN, ERIK, VERHAAK, ROEL GW · 2014 to 2017
$1.4M
NCI NIH HHS P01 CA085878NCI NIH HHS R01 CA190121
6 · The paper itself

Abstract

The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.

Indexed as

Genetic HeterogeneityHumansRhabdoid Tumormalignant rhabdoid tumorsmolecular analysispediatric cancersequencing

Identifiers

PMID28741508
PMCPMC5035037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.