Evidence map›Paper›PMID 28741410›Full record

ArticleMolecular pain

How can precision medicine be applied to temporomandibular disorders and its comorbidities?

Joan B Wilentz, Allen W Cowley

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Journal of dental research · 2021
    Trial
  2. Trial
  3. Review
  4. Review
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Joan B Wilentz1 The TMJ Association, Ltd., Milwaukee, WI, USA.
Allen W Cowley2 Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Medical College of Wisconsin · USTMJ Association · US

Funding

Role of trpv4 in trigeminally mediated nociceptionR01DE018549 · NIDCR · DUKE UNIVERSITY · PI LIEDTKE, WOLFGANG B. · 2007 to 2011
$2.5M
Biomedical Researcher Development Program in TMJD and Orofacial PainK12DE022793 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIM, PEI FENG, MAIXNER, WILLIAM · 2012 to 2016
$1.3M
Masticatory sensitization of trigeminal ganglion sensory neuronsF33DE024668 · NIDCR · DUKE UNIVERSITY · PI CHEN, YONG · 2014 to 2014
$53k
NIDCR NIH HHS F33 DE024668NIDCR NIH HHS K12 DE022793NIDCR NIH HHS R01 DE018549
6 · The paper itself

Abstract

The Eighth Scientific Meeting of The TMJ Association, Ltd. was held in Bethesda, Maryland, September 11-13, 2016. As in the past, the meeting was cosponsored by components of the National Institutes of Health with speakers invited to review the state of temporomandibular disorder science and propose recommendations to further progress. The theme of precision medicine, which aims to tailor disease treatment and prevention to match the characteristics of an individual patient (genetic, epigenetic, environmental, lifestyle) underscored the current consensus that temporomandibular disorders are no longer viewed as local conditions of jaw pain and dysfunction. Rather, they represent a complex family of biopsychosocial disorders that can progress to chronic pain, most often accompanied by one or more other chronic pain conditions. Temporomandibular disorders and these comorbidities, called chronic overlapping pain conditions, predominantly or exclusively affect women in their childbearing years and reflect central nervous system sensitization. Presenters at the meeting included leaders in temporomandibular disorder and pain research, temporomandibular disorder patients and advocates, and experts in other fields or in the use of technologies that could facilitate the development of precision medicine approaches in temporomandibular disorders.

Indexed as

Precision MedicineClinical Trials as TopicComorbidityEpigenesis, GeneticHumansPainSex CharacteristicsTemporomandibular Joint Disorderschronic overlapping pain conditionsPrecision medicinerecommendationstemporomandibular disordersTMJ Association

Identifiers

PMID28741410
PMCPMC5533261
OpenAlexW2738602473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.