ArticleIntegrative cancer therapies2018
Adherence to Mediterranean Diet and Metabolic Syndrome in BRCA Mutation Carriers.
Article in Integrative cancer therapies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Mediterranean-style diet for the primary and secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2019Pooled it
- How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in GermlineNutrients · 2023Trial
- Human Cancers Derived from Either Genetic or Lifestyle Factors Are Initiated by Impaired Estrogen Signaling.Cancers · 2025Review
- Complex Interplay Between Obesity and BRCA1/2-Associated Breast Cancer: An Overview.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Association between diet quality and malnutrition: pooled results from two population-based studies in older adults.BMC geriatrics · 2024Article
- Assessment of the Relationship between Periodontitis and Cardiac Parameters in Patients with Early Chronic Heart Failure: A Cross-Sectional Study.Journal of functional morphology and kinesiology · 2024Article
- Impact of home-based training and nutritional behavior on body composition and metabolic markers in cancer patients: data from the CRBP-TS study.Frontiers in nutrition · 2023Article
- miRNA deregulation and relationship with metabolic parameters after Mediterranean dietary intervention in BRCA-mutated women.Frontiers in oncology · 2023Article
- Mediterranean Diet and Atrial Fibrillation: Lessons Learned from the AFHRI Case-Control Study.Nutrients · 2022Article
- Physical activity and sleep behaviour in women carrying BRCA1/2 mutations.Scientific reports · 2022Article
- Article
- The Impact of Mediterranean Dietary Intervention on Metabolic and Hormonal Parameters According toFrontiers in genetics · 2022Article
- Physical activity and Mediterranean diet as potential modulators of osteoprotegerin and soluble RANKL in gBRCA1/2 mutation carriers: results of the lifestyle intervention pilot study LIBRE-1.Breast cancer research and treatment · 2021Article
- The Role of Health Literacy among Outpatient Caregivers during the COVID-19 Pandemic.International journal of environmental research and public health · 2021Article
- The Health Behaviour of German Outpatient Caregivers in Relation to the COVID-19 Pandemic: A Mixed-Methods Study.International journal of environmental research and public health · 2021Article
- Article
- BRCA1/2 Variants and Metabolic Factors: Results From a Cohort of Italian Female Carriers.Cancers · 2020Article
- Association between diet quality and obesity indicators among the working-age adults in Inner Mongolia, Northern China: a cross-sectional study.BMC public health · 2020Article
- Identification of predictive factors of the degree of adherence to the Mediterranean diet through machine-learning techniques.PeerJ. Computer science · 2020Article
- Association of serum lipids and severity of epithelial ovarian cancer: an observational cohort study of 349 Chinese patients.Journal of biomedical research · 2018Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsulin resistance is associated with higher breast cancer (BC) penetrance in BRCA mutation carriers. Metabolic syndrome (MetS), an insulin resistance syndrome, can be reversed by adhering to the Mediterranean diet (MedDiet). In a dietary intervention trial on BRCA mutation carriers, we evaluated adherence to the MedDiet, and the association with the MetS, by analyzing data from the Mediterranean Diet Adherence Screener (MEDAS).
methodsBRCA mutation carriers, with or without BC, aged 18 to 70 years, were eligible for the trial. After the baseline examinations, women were randomized to a dietary intervention or to a control group. Both groups completed the MEDAS at baseline and at the end of the dietary intervention.
resultsA total of 163 women completed the 6 months of dietary intervention. Compared with controls, the women in the intervention group significantly reduced their consumption of red meat ( P < .01) and commercial sweets ( P < .01) and their MEDAS score rose significantly (+1.3 vs +0.55, P = .02). The number of MetS parameters decreased with increasing points of adherence to the MEDAS score ( P = .01). In the intervention group, there was a significant association with the greater reduction of MetS.
conclusionBRCA mutation carriers in the intervention group experienced greater improvement in their MedDiet and MetS parameters.
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