Evidence map›Paper›PMID 28741316›Full record

ArticleEuropean journal of immunology2017

Role of CD4 T cell helper subsets in immune response and deviation of CD8 T cells in mice.

Alison Hogg, Yongjun Sui, Shlomo Z Ben-Sasson, William E Paul, Jay A Berzofsky

Open access · bronzeAbstract read
In one paragraph

Article in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. STK11 mutation affects tumor proliferation by impacting CD4Central-European journal of immunology · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 4 countries.

Alison HoggVaccine Branch, Center for Cancer Research, National Cancer Institute.
Yongjun SuiVaccine Branch, Center for Cancer Research, National Cancer Institute.ORCID 0000-0002-1568-4607
Shlomo Z Ben-SassonLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
William E PaulLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Jay A BerzofskyVaccine Branch, Center for Cancer Research, National Cancer Institute.
National Cancer Institute · UANational Institutes of Health · US

Funding

Vaccine and immunotherapy strategies for cancer and viruses causing cancerZIASC004020 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI BERZOFSKY, JAY A · 2009 to 2025
$51.8M
Interleukin 4ZIAAI000493 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GERMAIN, RONALD N · 2009 to 2017
$11.5M
Antigen-specific T-cell activation, vaccines for CancerZ01SC004020 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI BERZOFSKY, JAY A · 1996 to 2008
$3.8M
Intramural NIH HHS Z01 SC004020Intramural NIH HHS Z99 CA999999NCI NIH HHS Z01 SC004020
6 · The paper itself

Abstract

The ability of different CD4

Indexed as

AnimalsAntibodies, BlockingCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesEpitopes, T-LymphocyteFlow CytometryImmunity, CellularInterferon-gammaInterleukin-1betaMice, Inbred BALB CMice, Inbred C57BLTh17 CellsTh1 CellsT-Lymphocytes, Helper-InducerTransforming Growth Factor betaAntibodies, BlockingEpitopes, T-LymphocyteInterferon-gammaInterleukin-1betaTransforming Growth Factor betaIFN-γIL-1Immune deviationTc17TGF-βTh1Th17

Identifiers

PMID28741316
PMCPMC5886719
OpenAlexW2739303119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.